Does Radiofrequency Radiation From Mobile Phones Affect the Formation of Parotid Gland Malignancy? An Experimental Study.

Zerrin Ozergin Coskun, Levent Tumkaya, Adnan Yilmaz, Engin Dursun, Tolga Mercantepe, Yildiray Kalkan, Safak Ersoz
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Abstract

Objectives: The use of mobile phone is increasing around the world. Although it is beneficial in terms of communication, the electromagnetic radiations emitted by mobile phones may cause undesirable biological effects on the human body. In practical use, the tissue with which mobile phones come into most and are closest is the parotid gland. This study investigated the effects of the 1800 MHz electromagnetic field created by a generator on the parotid gland in rats. Methods: A total of 21 Sprague-Dawley Albino rats were included in the study. The rats were randomly divided into three equal groups. To simulate a mobile phone in conversation mode, the first study group was exposed to an 1800-MHz electromagnetic field for 6 hours a day for 30 days, and the second study group was exposed to an 1800-MHz electromagnetic field for 12 hours a day for 30 days. After 30 days, rats were sacrificed, and histopathological and immunohistochemical methods were used to evaluate the effects on the parotid gland. The total antioxidant level and the total oxidant level were measured biochemically in homogenized parotid tissue. Results: Histopathological results showed an increase in degeneration in rats exposed to electromagnetic fields for 6 and 12 hours a day, and immunohistochemical analysis showed an increase in the apoptotic index in both study groups (P = .001, P < .001). Intranuclear inclusions was observed during histopathological examination performed by electron microscopy. Conclusions: This study observed that the 1800 MHz electromagnetic field caused undesirable adverse histopathological and biochemical effects on the parotid gland of rats. Histopathological and biochemical findings were detected with increasing contact and exposure time. This study will lead to other studies on this topic and contribute to the literature by completing other studies.

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移动电话的射频辐射会影响腮腺恶性肿瘤的形成吗?一项实验研究。
目的:移动电话的使用在全球范围内日益增多。移动电话虽然有利于通信,但其发出的电磁辐射可能会对人体造成不良的生物影响。在实际使用中,手机接触最多、最接近的组织是腮腺。本研究调查了发生器产生的 1800 MHz 电磁场对大鼠腮腺的影响。研究方法研究共包括 21 只 Sprague-Dawley 白化大鼠。大鼠被随机分为三组。为了模拟手机通话模式,第一研究组每天暴露在 1800 兆赫电磁场中 6 小时,持续 30 天;第二研究组每天暴露在 1800 兆赫电磁场中 12 小时,持续 30 天。30 天后,大鼠被处死,采用组织病理学和免疫组织化学方法评估对腮腺的影响。在匀浆腮腺组织中对总抗氧化剂水平和总氧化剂水平进行生化测定。结果显示组织病理学结果表明,每天暴露在电磁场中 6 小时和 12 小时的大鼠腮腺变性增加,免疫组化分析表明两个研究组的凋亡指数都增加了(P = .001,P < .001)。用电子显微镜进行组织病理学检查时观察到核内包涵体。结论本研究观察到 1800 MHz 电磁场对大鼠腮腺造成了不良的组织病理学和生化影响。随着接触和暴露时间的增加,组织病理学和生物化学结果也随之增加。这项研究将引发有关该主题的其他研究,并通过完成其他研究为文献做出贡献。
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