Proportion of Peripheral Arterial Disease in Patients with Chronic Kidney Disease.

Mymensingh medical journal : MMJ Pub Date : 2024-10-01
M A Hamid, P K Datta, S Paul, M M Rahman, M A Rahaman, T A Sonali, T C Shil, Q Islam, M M Hakim
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Abstract

Among the different complications of chronic kidney diseases, peripheral arterial disease is not uncommon. Though it is an indicator of widespread atherosclerosis, sometimes it is neglected in CKD patients. Our study was done to evaluate the frequency and pattern of PAD in chronic kidney disease patients admitted in a tertiary care hospital of Bangladesh. One hundred (100) admitted patients of CKD were taken by nonrandom purposive sampling considering inclusion and exclusion criteria. After clinical evaluation and Ankle brachial index (ABI) measurement 5 cc venous blood was collected and sent to Clinical Pathology and Biochemistry department of CMCH. Data was collected in a structured proforma and analyzed. Among the 100 patients, 2.0% patient belonged to stage 3, 28.0% were in stage 4 and remaining 70.0% were in stage 5. We found the proportion of PAD in CKD were 18.0%. Among 18 PAD patients, 66.67% were in stage 5, 22.22% in stage 4 and 11.11% in stage 3. Regarding right lower limb 12 patients had some PAD, 3 patients had moderate PAD, 2 patients had borderline and 1 patient had calcified PAD. For left lower limb, 10 patients had some PAD, 4 patients had moderate PAD, 4 patients had borderline PAD. The mean AB) of the PAD patients for right limb was 0.87 and for left limb 0.84. 50.0-55.0% patients were asymptomatic. Among the PAD patients 38.9% had DM, 72.2% had HTN, 33.3% had both DM and HTN, 44.4% had other vascular events, 55.6% were smokers, 33.3% had dyslipidemia and 22.2% had family history of PAD. Renal diseases seem to have a strong association with vascular disease and PAD is not uncommon.

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慢性肾病患者的外周动脉疾病比例。
在慢性肾脏病的各种并发症中,外周动脉疾病并不少见。虽然它是广泛动脉粥样硬化的一个指标,但有时在慢性肾脏病患者中却被忽视。我们的研究旨在评估孟加拉国一家三级医院收治的慢性肾脏病患者中出现 PAD 的频率和模式。考虑到纳入和排除标准,我们采用非随机的目的性抽样方法,抽取了 100 名慢性肾脏病住院患者。在进行临床评估和踝肱指数(ABI)测量后,采集 5 cc 静脉血并送至孟加拉心脏病医院临床病理和生化科。通过结构化表格收集数据并进行分析。在 100 名患者中,2.0% 属于第三阶段,28.0% 属于第四阶段,其余 70.0% 属于第五阶段。我们发现 PAD 在 CKD 中的比例为 18.0%。在 18 名 PAD 患者中,66.67% 属于第 5 期,22.22% 属于第 4 期,11.11% 属于第 3 期。就右下肢而言,12 名患者有一些 PAD,3 名患者有中度 PAD,2 名患者有边缘 PAD,1 名患者有钙化 PAD。左下肢方面,10 名患者有部分 PAD,4 名患者有中度 PAD,4 名患者有边缘 PAD。右下肢 PAD 患者的平均 AB 值为 0.87,左下肢为 0.84。50.0%-55.0%的患者无症状。在 PAD 患者中,38.9% 的人患有糖尿病,72.2% 的人患有高血压,33.3% 的人同时患有糖尿病和高血压,44.4% 的人有其他血管事件,55.6% 的人吸烟,33.3% 的人血脂异常,22.2% 的人有 PAD 家族史。肾脏疾病似乎与血管疾病密切相关,而 PAD 并非罕见。
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