Comparison of ECMO, IABP and ECMO + IABP in the Postoperative Period in Patients with Postcardiotomy Shock.

IF 2.4 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Development and Disease Pub Date : 2024-09-08 DOI:10.3390/jcdd11090283
Cagdas Baran, Evren Ozcinar, Ahmet Kayan, Nur Dikmen, Canan Soykan Baran, Mustafa Bahadir Inan
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Abstract

Background: This study aims to assess the outcomes and complications of patients who received veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and intra-aortic balloon pump (IABP) support after cardiac surgery at Ankara University Heart Center between 2000 and 2023. Methods: We have carried out a retrospective analysis that included 255 patients. Among them, 98 received IABP, 103 received VA-ECMO, and 54 received both VA-ECMO and IABP. Preoperative and postoperative assessments were carried out, including evaluations of left ventricular function and serum creatinine levels. Primary outcomes included 30-day survival and successful VA-ECMO weaning. Complications such as bleeding, sepsis, liver failure, wound infection, and peripheral ischemia were also assessed. Results: The weaning rate from VA-ECMO was significantly higher in the combined VA-ECMO and IABP group (81.4%) compared with the other groups (p = 0.004). One-year survival was also higher in the combined group (75.9%) (p = 0.002). Complications or renal function did not differ significantly among the groups. The primary indication for mechanical support was coronary artery bypass grafting. Conclusions: In conclusion, the combined use of VA-ECMO and IABP therapy led to improved weaning and survival rates without increasing the risk of complications. These findings suggest that a combined approach may be beneficial for selected patients with severe cardiac dysfunction post surgery.

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心肌梗死术后休克患者术后使用 ECMO、IABP 和 ECMO + IABP 的比较。
研究背景本研究旨在评估 2000 年至 2023 年期间在安卡拉大学心脏中心接受静脉-动脉体外膜肺氧合(VA-ECMO)和主动脉内气囊泵(IABP)支持的心脏手术后患者的预后和并发症。方法:我们对 255 名患者进行了回顾性分析。其中 98 人接受了 IABP,103 人接受了 VA-ECMO,54 人同时接受了 VA-ECMO 和 IABP。我们进行了术前和术后评估,包括左心室功能和血清肌酐水平的评估。主要结果包括 30 天存活率和 VA-ECMO 成功断流。还对出血、败血症、肝功能衰竭、伤口感染和外周缺血等并发症进行了评估。结果VA-ECMO 和 IABP 联合组的 VA-ECMO 断流率(81.4%)明显高于其他组(p = 0.004)。联合组的一年存活率也更高(75.9%)(p = 0.002)。并发症或肾功能在各组间无明显差异。机械支持的主要适应症是冠状动脉旁路移植术。结论总之,联合使用 VA-ECMO 和 IABP 治疗可提高断血率和存活率,而不会增加并发症风险。这些研究结果表明,联合方法可能对术后严重心功能不全的特定患者有益。
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来源期刊
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.60
自引率
12.50%
发文量
381
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