Felix F Reichel, Peter Kiraly, Roopa Vemala, Stella Hornby, Samantha R De Silva, M Dominik Fischer
{"title":"Occlusive retinal vasculitis associated with intravitreal Faricimab injections.","authors":"Felix F Reichel, Peter Kiraly, Roopa Vemala, Stella Hornby, Samantha R De Silva, M Dominik Fischer","doi":"10.1186/s12348-024-00429-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.</p><p><strong>Methods: </strong>A retrospective case report.</p><p><strong>Results: </strong>A 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.</p><p><strong>Conclusion: </strong>Occlusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.</p>","PeriodicalId":16600,"journal":{"name":"Journal of Ophthalmic Inflammation and Infection","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11436497/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmic Inflammation and Infection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s12348-024-00429-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.
Methods: A retrospective case report.
Results: A 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.
Conclusion: Occlusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.
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