Impact of marmara-yegen cuttıng gastrojejunostomy on delayed gastrıc emptyıng after pancreatoduodenectomy: ınıtıal results.

IF 2.1 3区 医学 Q2 SURGERY Langenbeck's Archives of Surgery Pub Date : 2024-09-27 DOI:10.1007/s00423-024-03482-x
Ali Emre Atici, Ayşegul Bahar Ozocak, Ayse Eren Kayaci, Ecem Guclu Ozturk, Alper Kararmaz, Sevket Cumhur Yegen
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Abstract

Background: Delayed gastric emptying (DGE) is one of the most common reasons for morbidity after pancreatoduodenectomy. The technical characteristics of anastomosis that could be affected by surgeon may offer a relevant chance to improve postoperative DGE rates. We investigated the effect of a technical modification of gastrojejunostomy after the classical pancreaticoduodenectomy on DGE.

Materials and methods: A total of 161 patients underwent classical pancreaticoduodenectomy (with 20-40 percent antrectomy) due to pancreatic adenocarcinoma at the Department of General Surgery, Marmara University, School of Medicine Hospital, from February 2019 to May 2023, and those who met the inclusion criteria were enrolled. One hundred twenty patients had undergone classical end-to-side gastrojejunostomy (Classical GJ group), and 41 had undergone Marmara-Yegen cutting side-to-side gastrojejunostomy (M-Yc group). DGE was defined according to the International Working Group on Pancreatic Surgery, and postoperative DGE rates of both groups were compared. In addition, multivariate analysis was performed to identify possible independent predictive factors for DGE.

Results: The total incidence of DGE was 31% in the Classical GJ group and 17% in the (M-Yc group). Although there was no significant difference between the groups regarding DGE and DGE grades (p = 0.1), DGE was distinctly lower in the M-Yc GJ group. In multi-variant analysis, Clavien-Dindo grade 3a and above postoperative complication was determined as independent predictors for DGE.

Conclusions: We tried to explain the mechanism of DGE in terms of anatomical configuration. The incidence and severity of DGE decreased in patients who underwent M-Yc GJ.

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马尔马拉-耶根切胃空肠术对胰十二指肠切除术后延迟胃排空的影响:临床结果。
背景:胃排空延迟(DGE)是胰十二指肠切除术后最常见的发病原因之一。可受外科医生影响的吻合技术特点可能为提高术后 DGE 发生率提供相关机会。我们研究了经典胰十二指肠切除术后胃空肠吻合术的技术改造对 DGE 的影响:2019年2月至2023年5月期间,马尔马拉大学医学院附属医院普外科共对161例因胰腺癌接受经典胰十二指肠切除术(20%-40%反切除)的患者进行了登记,符合纳入标准的患者均被纳入其中。120名患者接受了经典的端侧胃空肠吻合术(经典GJ组),41名患者接受了马尔马拉-耶根切割侧对侧胃空肠吻合术(M-Yc组)。根据国际胰腺外科工作组对 DGE 的定义,比较了两组患者的术后 DGE 发生率。此外,还进行了多变量分析,以确定DGE可能的独立预测因素:经典 GJ 组的 DGE 总发生率为 31%,M-Yc 组为 17%。虽然两组在 DGE 和 DGE 等级方面没有明显差异(P = 0.1),但 M-Yc GJ 组的 DGE 明显较低。在多变量分析中,Clavien-Dindo 3a 级及以上术后并发症被确定为 DGE 的独立预测因素:我们试图从解剖结构的角度来解释 DGE 的机制。结论:我们试图从解剖结构的角度解释 DGE 的机制。接受 M-Yc GJ 的患者 DGE 的发生率和严重程度均有所下降。
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来源期刊
CiteScore
3.30
自引率
8.70%
发文量
342
审稿时长
4-8 weeks
期刊介绍: Langenbeck''s Archives of Surgery aims to publish the best results in the field of clinical surgery and basic surgical research. The main focus is on providing the highest level of clinical research and clinically relevant basic research. The journal, published exclusively in English, will provide an international discussion forum for the controlled results of clinical surgery. The majority of published contributions will be original articles reporting on clinical data from general and visceral surgery, while endocrine surgery will also be covered. Papers on basic surgical principles from the fields of traumatology, vascular and thoracic surgery are also welcome. Evidence-based medicine is an important criterion for the acceptance of papers.
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