Enhancing timing performance of heterostructures with double-sided readout.

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL Physics in medicine and biology Pub Date : 2024-10-08 DOI:10.1088/1361-6560/ad7fc8
Fiammetta Pagano, Nicolaus Kratochwil, Carsten Lowis, Woon-Seng Choong, Marco Paganoni, Marco Pizzichemi, Joshua W Cates, Etiennette Auffray
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Abstract

Objective.Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. These scintillators utilize alternating layers of materials with complementary properties to optimize performance. However, the layering compromises time resolution due to light transport issues. This study explores double-sided readout-enabling improved light collection and Depth-of-Interaction (DOI) information retrieval-to mitigate this effect and enhance the timing capabilities of heterostructures.Approach.The time resolution and DOI performances of 3 × 3 × 20 mm3BGO&EJ232 heterostructures were assessed in a single and double-sided readout (SSR and DSR, respectively) configuration using high-frequency electronics.Main results.Selective analysis of photopeak events yielded a DOI resolution of 6.4 ± 0.04 mm. Notably, the Coincidence Time Resolution (CTR) improved from 262 ± 8 ps (SSR) to 174 ± 6 ps (DSR) when measured in coincidence with a fast reference detector. Additionally, symmetrical configuration of two identical heterostructures in coincidence was tested, yielding in DSR a CTR of 254 ± 8 ps for all photopeak events and 107 ± 5 ps for the fastest events.Significance.By using high-frequency double-sided readout, we could measure DOI resolution and improve the time resolution of heterostructures of up to 40%. The DOI information resulted intrinsically captured in the average between the timestamps of the two SiPMs, without requiring any further correction.

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通过双面读取提高异质结构的计时性能。
异质结构闪烁体为平衡 TOF-PET 探测器的灵敏度和定时提供了一种很有前景的解决方案。这些闪烁体利用具有互补特性的交替材料层来优化性能。然而,由于光传输问题,分层会影响时间分辨率。本研究探讨了双面读出(可改善光收集和相互作用深度(DOI)信息检索),以减轻这种影响并增强异质结构的计时能力。对光峰事件的选择性分析得出的 DOI 分辨率为 6.4x0.04mm。值得注意的是,在与快速参考探测器重合测量时,重合时间分辨率(CTR)从 262±8 ps(SSR)提高到 174±6 ps(DSR)。此外,我们还测试了两个完全相同的异质结构的对称配置,在 DSR 中,所有光峰事件的 CTR 为 254±8 ps,最快事件的 CTR 为 107±5 ps。DOI 信息从两个 SiPM 的时间戳平均值中获得,无需进一步校正。
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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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