Feasibility and Exploration of a Standardized Protocol for Cardiac CT Assessment of Rheumatic Mitral Disease.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-09-10 eCollection Date: 2024-09-01 DOI:10.31083/j.rcm2509322
Zhou Liu, Yue Ren, Jiajun Liang, Yazhe Zhang, Hongkai Zhang, Maozhou Wang, Lei Xu, Yuyong Liu, Wenjian Jiang, Hongjia Zhang
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Abstract

Rheumatic mitral valve disease often requires surgical interventions, such as percutaneous mitral commissurotomy, surgical mitral valve repair, or replacement, especially in severe cases. This necessitates a precise preoperative assessment of the extent of mitral valve disease. Currently, transthoracic echocardiography, the gold standard for preoperative assessment, has limitations, such as restricted acoustic windows and dependence on the operator, which can affect the evaluation of subvalvular structures and calcification of the mitral valve. Previous studies have shown that cardiac computed tomography (CT), with its high resolution, strong multiplanar reconstruction capabilities, and sensitivity to calcifications, can effectively overcome these limitations. Therefore, this study aims to summarize and evaluate the effectiveness of cardiac CT in examining mitral valve leaflets, annulus, and subvalvular structures. It also reviews the feasibility and guiding significance of using cardiac CT to assess characteristic rheumatic mitral valve lesions.

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心脏 CT 评估风湿性二尖瓣病标准化方案的可行性与探索。
风湿性二尖瓣疾病通常需要外科干预,如经皮二尖瓣裂切开术、外科二尖瓣修复术或置换术,尤其是在严重病例中。这就需要在术前对二尖瓣病变的程度进行精确评估。目前,经胸超声心动图是术前评估的金标准,但它有其局限性,例如声窗受限和对操作者的依赖性,这可能会影响对瓣下结构和二尖瓣钙化的评估。以往的研究表明,心脏计算机断层扫描(CT)具有分辨率高、多平面重建能力强、对钙化敏感等特点,可以有效克服这些局限性。因此,本研究旨在总结和评估心脏 CT 在检查二尖瓣瓣叶、瓣环和瓣下结构方面的有效性。研究还回顾了使用心脏 CT 评估风湿性二尖瓣特征性病变的可行性和指导意义。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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