Hong Yin, Vilma Blomberg, LiWei Sun, ChunXia Yin, Susanne Sütterlin
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引用次数: 0
Abstract
Objective: The aim of the study was to investigate the virulence factors in Escherichia coli producing extended-spectrum beta-lactamase (ESBL) derived from the perinatal fecal colonization flora of mothers and their newborns in a Chinese obstetric ward.
Study design: Rectal swabs were obtained from mothers prenatally and from their newborns postnatally, and analyzed for ESBL-producing E. coli. The isolates were then whole-genome sequenced.
Results: Maternal and neonatal colonization by extended spectrum beta-lactamase (ESBL)-producing E. coli in a Chinese obstetric ward was 18% (31/177) and 5% (9/170), respectively. Fecal ESBL-producing isolates exhibited a significantly lower frequency of virulence factors compared to invasive E. coli.
Conclusion: Providing balanced information on screening results is essential, along with conducting a risk assessment for antibiotic treatment strategies.
期刊介绍：
The American Journal of Perinatology is an international, peer-reviewed, and indexed journal publishing 14 issues a year dealing with original research and topical reviews. It is the definitive forum for specialists in obstetrics, neonatology, perinatology, and maternal/fetal medicine, with emphasis on bridging the different fields.
The focus is primarily on clinical and translational research, clinical and technical advances in diagnosis, monitoring, and treatment as well as evidence-based reviews. Topics of interest include epidemiology, diagnosis, prevention, and management of maternal, fetal, and neonatal diseases. Manuscripts on new technology, NICU set-ups, and nursing topics are published to provide a broad survey of important issues in this field.
All articles undergo rigorous peer review, with web-based submission, expedited turn-around, and availability of electronic publication.
The American Journal of Perinatology is accompanied by AJP Reports - an Open Access journal for case reports in neonatology and maternal/fetal medicine.
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