Near-fatal pheochromocytoma crisis after beta-blocker and tumour haemorrhage.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL BMJ Case Reports Pub Date : 2024-10-02 DOI:10.1136/bcr-2024-260870
Divya Madhavarapu, Anthony Asta, Gizem Reyhanoglu, Antoni Kafrouni Gerges
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Abstract

Pheochromocytomas are rare neuroendocrine tumors characterised by the secretion of catecholamines and their metabolites. While some patients may be asymptomatic, they can also present with various symptoms including hypertensive crisis, headaches, palpitations, diaphoresis or other signs of catecholamine toxicity. Adrenal haemorrhage, though rare, is a potentially fatal complication that is often diagnosed during autopsy. In all patients with suspected pheochromocytoma, regardless of whether haemorrhagic conversion has occurred, prompt diagnosis is imperative. Early identification allows for the timely initiation of treatment, preventing potentially life-threatening complications. This case report details the haemorrhagic conversion of an undiagnosed pheochromocytoma in a female patient in her 30s.

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β-受体阻滞剂和肿瘤出血后嗜铬细胞瘤危象,几近死亡。
嗜铬细胞瘤是一种罕见的神经内分泌肿瘤,以分泌儿茶酚胺及其代谢产物为特征。有些患者可能没有症状,但也可能出现各种症状,包括高血压危象、头痛、心悸、全身舒张或其他儿茶酚胺中毒症状。肾上腺出血虽然罕见,但却是一种潜在的致命并发症,通常在尸检时才能确诊。对于所有疑似嗜铬细胞瘤的患者,无论是否发生出血转化,都必须及时诊断。早期发现可以及时开始治疗,防止出现可能危及生命的并发症。本病例报告详细描述了一名 30 多岁女性患者因未确诊嗜铬细胞瘤而发生出血性转化的情况。
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来源期刊
BMJ Case Reports
BMJ Case Reports Medicine-Medicine (all)
CiteScore
1.40
自引率
0.00%
发文量
1588
期刊介绍: BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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