{"title":"Vitamin C and its derivatives in maintaining the good skin condition","authors":"Urszula Goik","doi":"10.18388/pb.2021_554","DOIUrl":null,"url":null,"abstract":"<p><p>Vitamin C is one of the most important and necessary nutrient for human health, which has great potential as cosmeceutic, which protects health and the skin good condition. Thru the collagen biosynthesis stimulation it affects to the physiology of human skin, participating in the hydroxylation process of proline and lysine, and participates in tissue reconstruction while wound healing. Deficiency of vitamin C causes irregularities in the blood vessels functioning, epidermis and dermis. Is an effective antioxidant neutralizing free radicals, prevents inflammatory and carcinogenic processes. The epidermis and dermis are most exposed to free radicals from the external environment and from the inside of the body. In inflammatory diseases of the skin, such as atopic dermatitis, psoriasis, in the proper skin the levels of vitamin C are reduced. Therefore, delivering it to the skin using cosmetic preparations is important not only for cosmetic, but also health effect. The problem associated with the introduction of vitamin C in cosmetics is its limited penetration through the stratum corneum. Current studies are focused on searching for stable compounds of ascorbic acid and new media, which will allow for better way of delivery of ascorbic acid to the dermis in the future.</p>","PeriodicalId":20335,"journal":{"name":"Postepy biochemii","volume":"70 3","pages":"307-314"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Postepy biochemii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18388/pb.2021_554","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/30 0:00:00","PubModel":"Print","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Vitamin C is one of the most important and necessary nutrient for human health, which has great potential as cosmeceutic, which protects health and the skin good condition. Thru the collagen biosynthesis stimulation it affects to the physiology of human skin, participating in the hydroxylation process of proline and lysine, and participates in tissue reconstruction while wound healing. Deficiency of vitamin C causes irregularities in the blood vessels functioning, epidermis and dermis. Is an effective antioxidant neutralizing free radicals, prevents inflammatory and carcinogenic processes. The epidermis and dermis are most exposed to free radicals from the external environment and from the inside of the body. In inflammatory diseases of the skin, such as atopic dermatitis, psoriasis, in the proper skin the levels of vitamin C are reduced. Therefore, delivering it to the skin using cosmetic preparations is important not only for cosmetic, but also health effect. The problem associated with the introduction of vitamin C in cosmetics is its limited penetration through the stratum corneum. Current studies are focused on searching for stable compounds of ascorbic acid and new media, which will allow for better way of delivery of ascorbic acid to the dermis in the future.
维生素 C 是人体健康最重要和最必需的营养素之一,具有很大的美容潜力,可保护健康和皮肤的良好状态。它通过刺激胶原蛋白的生物合成影响人体皮肤的生理机能,参与脯氨酸和赖氨酸的羟化过程,并在伤口愈合时参与组织重建。缺乏维生素 C 会导致血管功能、表皮和真皮出现异常。维生素 C 是一种有效的抗氧化剂,能中和自由基,防止炎症和致癌过程。表皮和真皮最容易受到来自外部环境和身体内部的自由基的影响。在皮肤炎症性疾病中,如特应性皮炎、牛皮癣,正常皮肤中的维生素 C 水平会降低。因此,使用化妆品向皮肤输送维生素 C 不仅对美容很重要,对健康也很重要。在化妆品中引入维生素 C 的相关问题是其在角质层中的渗透力有限。目前的研究重点是寻找稳定的抗坏血酸化合物和新介质,以便将来能以更好的方式将抗坏血酸输送到真皮层。