Predicting non-response to intraglandular botulinum neurotoxin A injections for drooling in children with neurodevelopmental disabilities

IF 4.3 2区 医学 Q1 CLINICAL NEUROLOGY Developmental Medicine and Child Neurology Pub Date : 2024-10-03 DOI:10.1111/dmcn.16101
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Abstract

Drooling can greatly affect the daily lives of children with neurodevelopmental disabilities. Botox injections into the saliva glands can help reduce drooling. Doctors are uncertain whether to treat only the submandibular glands under the jaw or also the parotid glands near the ears. The goal of this study was to predict which children might not respond well to these injections (no large reduction in drooling), to decide on the best treatment approach.

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预测神经发育障碍儿童对腺内注射 A 型肉毒杆菌神经毒素治疗流口水无效的情况。
流口水会严重影响神经发育障碍儿童的日常生活。向唾液腺注射肉毒杆菌毒素有助于减少流口水。医生们还不确定是只治疗颌下的颌下腺,还是也治疗耳朵附近的腮腺。这项研究的目的是预测哪些儿童可能对这些注射反应不佳(流口水现象没有明显减少),从而决定最佳的治疗方法。
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来源期刊
CiteScore
7.80
自引率
13.20%
发文量
338
审稿时长
3-6 weeks
期刊介绍: Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA). For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.
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