Xiaolin Xie, Shuang Wang, Zhi Chen, Yifan Yu, Xiaoxue Hu, Ningning Ma, Min Ji, Ye Tian
{"title":"Exploring DNA Computers: Advances in Storage, Cryptography and Logic Circuits.","authors":"Xiaolin Xie, Shuang Wang, Zhi Chen, Yifan Yu, Xiaoxue Hu, Ningning Ma, Min Ji, Ye Tian","doi":"10.1002/cbic.202400670","DOIUrl":null,"url":null,"abstract":"<p><p>Over the last four decades, research on DNA as a functional material has primarily focused on its predictable conformation and programmable interaction. However, its low energy consumption, high responsiveness and sensitivity also make it ideal for designing specific signaling pathways, and enabling the development of molecular computers. This review mainly discusses recent advancements in the utilization of DNA nanotechnology for molecular computer, encompassing applications in storage, cryptography and logic circuits. It elucidates the challenges encountered in the application process and presents solutions exemplified by representative works. Lastly, it delineates the challenges and opportunities within this filed.</p>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1002/cbic.202400670","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
Over the last four decades, research on DNA as a functional material has primarily focused on its predictable conformation and programmable interaction. However, its low energy consumption, high responsiveness and sensitivity also make it ideal for designing specific signaling pathways, and enabling the development of molecular computers. This review mainly discusses recent advancements in the utilization of DNA nanotechnology for molecular computer, encompassing applications in storage, cryptography and logic circuits. It elucidates the challenges encountered in the application process and presents solutions exemplified by representative works. Lastly, it delineates the challenges and opportunities within this filed.
在过去的四十年里,对 DNA 这种功能材料的研究主要集中在其可预测的构象和可编程的相互作用上。然而,DNA 的低能耗、高响应性和灵敏度也使其成为设计特定信号通路和开发分子计算机的理想材料。这篇综述主要讨论了利用 DNA 纳米技术制造分子计算机的最新进展,包括在存储、密码学和逻辑电路方面的应用。它阐明了在应用过程中遇到的挑战,并通过代表性作品介绍了解决方案。最后,它描述了这一领域所面临的挑战和机遇。