Calcifying cystic odontogenic tumour: Dilemma and pitfalls.

IF 2.9 3区 医学 Q2 MEDICAL LABORATORY TECHNOLOGY Seminars in Diagnostic Pathology Pub Date : 2024-09-19 DOI:10.1053/j.semdp.2024.09.005
Arushi Tomar, Sharon John, Saloni Verma, Shalini Gupta
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Abstract

Odontogenic lesions are a category of lesions, which are found to be arising from the remnants of the tooth-bearing tissues of the body, that can be cystic in nature as a result of degeneration or as a result of excessive proliferation of these cells, can result in the formation of odontogenic tumours which are found in gnathic bones in the body. Since their discovery in literature and the explanation provided for their pathogenesis, these lesions have been the subject of debate and controversy amongst researchers as well as practitioners. Thereby, this review has taken into consideration one such odontogenic tumour, Calcifying Cystic Odontogenic Tumour (CCOT), which first were included under the namesake (Calcifying odontogenic cyst) as a sperate subheading under this cyst, but now has been designated under the category of tumours along with various histologic subtypes classified and described henceforth. Although the lesion has been removed in the recent classification, a wide variety of lesions in biphasic form has been reported in the past. Therefore, this present review takes a sneak-peek into this lesion with insight into its presentation, incidence, aetiology, pathogenesis, histopathology and all the controversies surrounding this category of lesion and the current literature about this lesion with proving the fact that this needs to be considered again in the category of odontogenic tumours.

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钙化性囊性牙源性肿瘤:困境与陷阱
牙源性病变是一类病变,产生于人体残余的牙组织,由于这些细胞的变性或过度增殖,可能形成囊性病变,也可能形成牙源性肿瘤,这些肿瘤存在于人体的颌骨中。自从在文献中发现这些病变并对其发病机理做出解释以来,这些病变一直是研究人员和从业人员争论和争议的主题。钙化性囊性牙源性肿瘤(CCOT)最初作为 "钙化性囊性牙源性囊肿 "的一个独立小标题,被归入 "肿瘤 "的范畴,并对其组织学亚型进行了分类和描述。虽然在最近的分类中,该病变已被删除,但过去曾报道过多种双相形式的病变。因此,本综述将对这一病变进行深入探讨,包括其表现、发病率、病因、发病机制、组织病理学以及围绕这类病变的所有争议和有关这一病变的现有文献,并证明这一事实,即需要在牙源性肿瘤类别中再次考虑这一病变。
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来源期刊
CiteScore
4.80
自引率
0.00%
发文量
69
审稿时长
71 days
期刊介绍: Each issue of Seminars in Diagnostic Pathology offers current, authoritative reviews of topics in diagnostic anatomic pathology. The Seminars is of interest to pathologists, clinical investigators and physicians in practice.
期刊最新文献
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