Remission of Acromegaly: The Sooner the Better

IF 2.4 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Clinical Endocrinology Pub Date : 2024-10-07 DOI:10.1111/cen.15147
Thomas Cuny, Luigi Maione, Sylvère Störmann
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Abstract

Remission of acromegaly is defined by normalization of GH/IGF-1 values according to age and gender. While treatment strategies, biochemical cut-off to reach, and morbidities related to the persistence of the disease are well described in the literature, there is little data focusing on the delay to reach remission and its consequences. In this commentary, the authors discussed the results obtained from the UK acromegaly registry showing that the time to biochemical remission predicts the overall survival of patients in acromegaly.

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肢端肥大症的缓解:越快越好
根据年龄和性别,肢端肥大症缓解的定义是 GH/IGF-1 值恢复正常。虽然治疗策略、达到的生化临界值以及与疾病持续存在相关的发病率在文献中有详细描述,但很少有数据关注达到缓解的延迟及其后果。在这篇评论中,作者讨论了英国肢端肥大症登记的结果,结果显示生化缓解时间可预测肢端肥大症患者的总体生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Endocrinology
Clinical Endocrinology 医学-内分泌学与代谢
CiteScore
6.40
自引率
3.10%
发文量
192
审稿时长
1 months
期刊介绍: Clinical Endocrinology publishes papers and reviews which focus on the clinical aspects of endocrinology, including the clinical application of molecular endocrinology. It does not publish papers relating directly to diabetes care and clinical management. It features reviews, original papers, commentaries, correspondence and Clinical Questions. Clinical Endocrinology is essential reading not only for those engaged in endocrinological research but also for those involved primarily in clinical practice.
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