Effects of traditional Chinese medicine on symptoms of patients with spleen and stomach deficiency-related tinnitus.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL World Journal of Clinical Cases Pub Date : 2024-10-06 DOI:10.12998/wjcc.v12.i28.6165

Na Cui, Chen Zhao, Jun-Lai Xue, Xue-Wei Zhu

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Abstract

Background: Tinnitus affects 10%-30% of the population. Recent evidence suggests that tinnitus is associated with spleen deficiency. However, compared with kidney deficiency-related tinnitus, less research has been conducted on the impact of spleen deficiency-related tinnitus.

Aim: To investigate the clinical efficacy of using Guipi Wan and dietary and lifestyle modification based on traditional Chinese medicine for treatment of patients with spleen and stomach deficiency-related tinnitus.

Methods: We enrolled 110 patients with spleen and stomach deficiency-related tinnitus who were distributed into treatment (58 cases) and control (52 cases) groups. Tinnitus severity, sleep quality and emotional state were assessed by questionnaires [Tinnitus Evaluation Questionnaire (TEQ); Pittsburgh Sleep Quality Index (PSQI); Depression-Anxiety-Stress Scale-21 (DASS-21)] that were used for analysis in the two groups during the initial and intervention and after. In the treatment group, patients were treated with oral administration of Guipi Wan and consulted for healthy dietary and lifestyle modification. In the control group, patients were only assessed and not treated.

Results: At the end of the 6-months, TEQ scores decreased significantly in the treatment group (P = 0.021) but not in the Control group. Significant effects in the treatment group were noted for PSQI total score (P = 0.043) and several PSQI component scores in the treatment group (P < 0.05). After treatment, the DASS-21 scores were significantly reduced in the treatment group (P < 0.05).

Conclusion: Guipi Wan combined with dietary and lifestyle modification based on regulating the spleen and stomach can be considered core to the treatment of tinnitus related to spleen and stomach deficiency.

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中药对脾胃虚弱型耳鸣患者症状的影响

背景介绍耳鸣患者占总人口的 10%-30%。最近的证据表明，耳鸣与脾虚有关。摘要：目的：探讨桂附丸配合中药饮食调理治疗脾胃虚弱型耳鸣的临床疗效：110例脾胃虚弱型耳鸣患者分为治疗组（58例）和对照组（52例）。采用耳鸣评估问卷（TEQ）、匹兹堡睡眠质量指数（PSQI）、抑郁-焦虑-压力量表-21（DASS-21））对两组患者的耳鸣严重程度、睡眠质量和情绪状态进行评估，并对两组患者在初始治疗和干预期间及干预后的情况进行分析。治疗组患者接受桂皮丸口服治疗，并接受健康饮食和生活方式调整咨询。在对照组中，患者只接受评估而不接受治疗：结果：6 个月结束时，治疗组的 TEQ 分数明显下降（P = 0.021），而对照组则没有。治疗组的 PSQI 总分（P = 0.043）和几个 PSQI 组成分数（P < 0.05）均有明显效果。治疗后，治疗组的 DASS-21 评分明显降低（P < 0.05）：结论：桂附丸结合以调理脾胃为主的饮食与生活调理，是治疗脾胃虚弱型耳鸣的核心方。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

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3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.