[Livedo reticularis following administration of COVID-19 vaccine: a case report].

IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pan African Medical Journal Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI:10.11604/pamj.2024.49.9.31779
Meryem Ouhaddach, Mouna Zahlane, Lamiaâ Essaadouni
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Abstract

The emergence of severe acute respiratory syndrome coronavirus 2 has made it crucial to develop safe vaccines. Three main types of vaccines are currently available. Although they have proven to be very secure, they have caused various adverse effects. We here report a rare case of livedo reticularis following the administration of COVID-19 vaccine in a 54-year-old woman. It occurred 24 hours after vaccination, accompanied by respiratory, digestive, and neurological disorders and deterioration in general condition. Examinations revealed skin lesions compatible with livedo reticularis, mild inflammatory syndrome and hypercholesterolemia. Imaging showed no abnormalities. Immunological tests were positive for lupus anticoagulant. The patient received symptomatic treatment, with improvement in neurological and joint symptoms and a slight regression of skin rashes. After three months, the lupus anticoagulant test remained positive, confirming post-vaccination antiphospholipid syndrome (APS). The association of livedo reticularis with COVID-19 vaccine should not be underestimated and its degree of severity remains to be determined. More data and cases need to be collected for a more in-depth and detailed analysis.

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[接种 COVID-19 疫苗后出现的网状生命体征:病例报告]。
严重急性呼吸系统综合症冠状病毒 2 的出现使得开发安全疫苗变得至关重要。目前主要有三种疫苗。尽管这些疫苗已被证明非常安全,但它们也引起了各种不良反应。我们在此报告了一例罕见病例,一名 54 岁的女性在接种 COVID-19 疫苗后出现了网状组织活检。该病例发生在接种疫苗 24 小时后,同时伴有呼吸道、消化道和神经系统紊乱以及全身状况恶化。检查发现皮肤病变与活组织网状结构症、轻度炎症综合征和高胆固醇血症相符。影像学检查未发现异常。免疫学检查显示狼疮抗凝物呈阳性。患者接受了对症治疗,神经和关节症状有所改善,皮疹略有消退。三个月后,狼疮抗凝物检测仍呈阳性,证实了接种疫苗后抗磷脂综合征(APS)。不应低估网状组织活化症与 COVID-19 疫苗的关系,其严重程度仍有待确定。需要收集更多的数据和病例,以便进行更深入、更详细的分析。
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来源期刊
Pan African Medical Journal
Pan African Medical Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.80
自引率
0.00%
发文量
691
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