Acute severe hepatitis and COVID-19: case report.

IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pan African Medical Journal Pub Date : 2024-09-02 eCollection Date: 2024-01-01 DOI:10.11604/pamj.2024.49.2.44247
Saber Hmimass, Maryeme Kadiri, Mohamed Borahma, Fatima-Zahra Chabib, Camelia Berhili, Nawa Lagdali, Imane Ben Elbarhdadi, Fatima-Zahra Ajana
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Abstract

COVID-19, caused by SARS-CoV-2, has been declared an international public health emergency. Patients with COVID-19, even without a history of liver disease, frequently present with liver test disturbances. Due to the multisystemic involvement of COVID-19, the pathogenesis of liver injury is likely to be multifactorial, involving systemic inflammation, small vessel thrombosis, hepatic hypoxia, and potential drug toxicity, ruling out direct infection of hepatocytes by SARS-CoV-2. COVID-19 can cause severe acute hepatitis. We report the case of a 25-year-old man admitted to emergency with abdominal pain who presented with acute severe liver failure before respiratory signs.

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急性重症肝炎与 COVID-19:病例报告。
由 SARS-CoV-2 引起的 COVID-19 已被宣布为国际公共卫生紧急事件。COVID-19 患者即使没有肝病史,也会经常出现肝脏检查紊乱。由于 COVID-19 涉及多个系统,肝损伤的发病机制可能是多因素的,涉及全身炎症、小血管血栓形成、肝缺氧和潜在的药物毒性,排除了 SARS-CoV-2 直接感染肝细胞的可能性。COVID-19 可引起严重的急性肝炎。我们报告了一例因腹痛急诊入院的 25 岁男性病例,他在出现呼吸征兆之前就出现了急性重症肝衰竭。
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来源期刊
Pan African Medical Journal
Pan African Medical Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.80
自引率
0.00%
发文量
691
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