Impacts of risk-stratified inpatient penicillin allergy label delabeling on subsequent antimicrobial spectrum index and costs.

Milner Staub, George E Nelson, Kelly Byrge, Grace Koo, Whitney J Nesbitt, Joanna L Stollings, Minhua Zhang, Cosby A Stone
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Abstract

Penicillin allergy delabeling may benefit antimicrobial stewardship (AS). Cost of initial penicillin treatments following risk-stratified inpatient delabeling were compared to two hypothetical treatment regimens if delabeling had not occurred: (1) AS-guided and (2) Common Treatment. Penicillin allergy delabeling improved antimicrobial spectrum index, was cost-neutral, and averted unnecessary penicillin desensitizations.

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住院病人青霉素过敏标签风险分级对后续抗菌谱指数和成本的影响。
取消青霉素过敏标签可能有利于抗菌药物管理(AS)。将风险分层的住院病人脱标后初始青霉素治疗的成本与未脱标情况下的两种假设治疗方案进行了比较:(1) AS 指导下的治疗方案;(2) 普通治疗方案。青霉素过敏脱标改善了抗菌谱指数,不增加成本,并避免了不必要的青霉素脱敏。
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