Chengye Zhang, Lizhuang Han, Kemeng Dong, Qin Zhang, Zhihua Liu
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引用次数: 0
Abstract
replying to A. Tasegian et al. Nature Immunology https://doi.org/10.1038/s41590-024-01972-0 (2024)
We read the comments by Tasegian et al. related to our article published in Nature Immunology, entitled ‘Commensal bacteria direct selective cargo sorting to promote symbiosis’1, with keen interest. In Zhang et al.1, we reported a Nod2-LRRK2-dependent lysozyme-sorting phenomenon in Paneth cells. Tasegian et al.2 noted no change in lysozyme staining in Lrrk2−/− mice and the absence of leucine-rich repeat kinase 2 (LRRK2) on Paneth cell granules.
期刊介绍：
Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.
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