Current management of hepatobiliary malignancies between centers with or without a liver transplant program: A multi-society national survey.

IF 4 3区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Digestive and Liver Disease Pub Date : 2024-10-07 DOI:10.1016/j.dld.2024.09.007
Matteo Serenari, Roberta Angelico, Quirino Lai, Damiano Patrono, Irene Scalera, Emanuele Kauffmann, Duilio Pagano, Riccardo De Carlis, Enrico Gringeri, Alessandro Vitale
{"title":"Current management of hepatobiliary malignancies between centers with or without a liver transplant program: A multi-society national survey.","authors":"Matteo Serenari, Roberta Angelico, Quirino Lai, Damiano Patrono, Irene Scalera, Emanuele Kauffmann, Duilio Pagano, Riccardo De Carlis, Enrico Gringeri, Alessandro Vitale","doi":"10.1016/j.dld.2024.09.007","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Availability of liver transplantation (LT) as a treatment for hepatocellular carcinoma (HCC) and other liver malignancies may determine heterogeneity of therapeutic strategies across different centers.</p><p><strong>Aims: </strong>To investigate the practice between hepato-biliary centers without (HB centers) and with a LT program (LT centers), we launched a 38-item web-based national survey, with directors of centers as a target.</p><p><strong>Methods: </strong>The survey, including 4 clinical vignettes, collected data on their approach to HCC and transplant oncology.</p><p><strong>Results: </strong>After duplicates removal, 75 respondents were considered. Respondents from LT centers (n = 22, 29.3 %) were more in favor of LT in the case of HCC outside Milan criteria (90.9 % vs. 67.9 %, p = 0.037), recurrent HCC (95.5 % vs. 50.9 %, p = 0.002) and other malignancies such as cholangiocarcinoma or neuroendocrine tumors. No significant difference was observed concerning the proportion of centers favorable to LT for unresectable colorectal liver metastases (100 % vs. 88.7 %, p = 0.100).</p><p><strong>Conclusion: </strong>This national survey showed how management of HCC and awareness of transplant oncology may differ between HB and LT centers. Effective networking between HB and LT centers is crucial to provide optimal treatment and access to LT.</p>","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":null,"pages":null},"PeriodicalIF":4.0000,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Digestive and Liver Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.dld.2024.09.007","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Availability of liver transplantation (LT) as a treatment for hepatocellular carcinoma (HCC) and other liver malignancies may determine heterogeneity of therapeutic strategies across different centers.

Aims: To investigate the practice between hepato-biliary centers without (HB centers) and with a LT program (LT centers), we launched a 38-item web-based national survey, with directors of centers as a target.

Methods: The survey, including 4 clinical vignettes, collected data on their approach to HCC and transplant oncology.

Results: After duplicates removal, 75 respondents were considered. Respondents from LT centers (n = 22, 29.3 %) were more in favor of LT in the case of HCC outside Milan criteria (90.9 % vs. 67.9 %, p = 0.037), recurrent HCC (95.5 % vs. 50.9 %, p = 0.002) and other malignancies such as cholangiocarcinoma or neuroendocrine tumors. No significant difference was observed concerning the proportion of centers favorable to LT for unresectable colorectal liver metastases (100 % vs. 88.7 %, p = 0.100).

Conclusion: This national survey showed how management of HCC and awareness of transplant oncology may differ between HB and LT centers. Effective networking between HB and LT centers is crucial to provide optimal treatment and access to LT.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
有肝移植计划或没有肝移植计划的中心对肝胆恶性肿瘤的管理现状:多学会全国调查。
背景:目的:为了调查没有肝移植项目的肝胆中心(HB中心)和有肝移植项目的肝胆中心(LT中心)之间的实践情况,我们以各中心主任为对象,开展了一项包含38个项目的全国性网络调查:调查包括 4 个临床小故事,收集了有关 HCC 和移植肿瘤学方法的数据:结果:去除重复数据后,共有 75 名受访者。来自LT中心的受访者(n = 22,29.3%)更倾向于LT治疗米兰标准以外的HCC(90.9% vs. 67.9%,p = 0.037)、复发性HCC(95.5% vs. 50.9%,p = 0.002)以及胆管癌或神经内分泌肿瘤等其他恶性肿瘤。对于无法切除的结直肠肝转移瘤,接受LT治疗的中心比例无明显差异(100% vs. 88.7%,p = 0.100):这项全国性调查显示,肝转移癌和肝癌晚期治疗中心对肝转移癌的管理以及对移植肿瘤学的认识可能存在差异。HB 和 LT 中心之间建立有效的网络联系对于提供最佳治疗和获得 LT 至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Digestive and Liver Disease
Digestive and Liver Disease 医学-胃肠肝病学
CiteScore
6.10
自引率
2.20%
发文量
632
审稿时长
19 days
期刊介绍: Digestive and Liver Disease is an international journal of Gastroenterology and Hepatology. It is the official journal of Italian Association for the Study of the Liver (AISF); Italian Association for the Study of the Pancreas (AISP); Italian Association for Digestive Endoscopy (SIED); Italian Association for Hospital Gastroenterologists and Digestive Endoscopists (AIGO); Italian Society of Gastroenterology (SIGE); Italian Society of Pediatric Gastroenterology and Hepatology (SIGENP) and Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD). Digestive and Liver Disease publishes papers on basic and clinical research in the field of gastroenterology and hepatology. Contributions consist of: Original Papers Correspondence to the Editor Editorials, Reviews and Special Articles Progress Reports Image of the Month Congress Proceedings Symposia and Mini-symposia.
期刊最新文献
Recent trends in foreign body ingestion (FBI) epidemiology: A national cohort study. Duodenal gastric heterotopia diagnosed by spectral CT. Feasibility, safety and efficacy of endoscopic submucosal dissection for recurrent superficial rectal neoplastic lesions after transanal microsurgery. Liver transplant for hepatocellular carcinoma in metabolic dysfunction-associated steatotic liver disease versus other etiologies: A meta-analysis. Sarcopenia in patients receiving TIPS is independently associated with increased risk of complications and mortality.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1