[Application of zinc agents in Wilson's disease].

C Liang, W Hou, Z P Duan, S J Zheng
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引用次数: 0

Abstract

Wilson's disease (WD) is a kind of inherited metabolic liver disease in which most patients need lifelong medication to maintain copper homeostasis in the body. Zinc is one of the most commonly used drugs for WD treatment. However, there are currently few high-quality, large-sample, and prospective clinical trials on zinc agent-treated WD. The selection and application of zinc agents are mainly based on patients' clinical phenotype, tolerance to zinc agents, and physicians' experience in treating WD. This article summarizes the application of zinc agents in WD.

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[锌制剂在威尔逊氏病中的应用]。
威尔逊氏病(WD)是一种遗传性代谢性肝病,大多数患者需要终身服药来维持体内铜的平衡。锌是治疗威尔森氏病最常用的药物之一。然而,目前关于锌剂治疗 WD 的高质量、大样本和前瞻性临床试验还很少。锌制剂的选择和应用主要基于患者的临床表型、对锌制剂的耐受性以及医生治疗 WD 的经验。本文总结了锌制剂在 WD 中的应用。
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来源期刊
中华肝脏病杂志
中华肝脏病杂志 Medicine-Medicine (all)
CiteScore
1.20
自引率
0.00%
发文量
7574
期刊介绍:
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[A case of giant hilar cholangiocarcinoma accompanied by hyperbilirubinemia achieved disease stabilization via hepatic artery infusion chemotherapy combined with targeted therapy]. [A mechanistic study of radiotherapy on intratumoral NK cell infiltration augmentation by regulating the EZH2/CXCL10 pathway in hepatocellular carcinoma cells]. [A nomogram prediction model for individualized prediction of the risk of covert (minimal) hepatic encephalopathy occurrence in patients with liver cirrhosis]. [Analysis of the etiology and clinical indicators of infantile cholestasis]. [Application of zinc agents in Wilson's disease].
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