{"title":"RESOLUTION OF MACULAR CONFLUENT DRUSEN DURING THE DEVELOPMENT AND SPONTANEOUS CLOSURE OF AN ECCENTRIC FULL-THICKNESS MACULAR HOLE.","authors":"Shuichiro Aoki, Kohei Ueda, Kohdai Kitamoto, Keiko Azuma, Ryo Obata","doi":"10.1097/ICB.0000000000001658","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to describe a unique case of drusen resolution accompanying the spontaneous closure of an eccentric full-thickness macular hole.</p><p><strong>Methods: </strong>This study is a case report.</p><p><strong>Results: </strong>A 71-year-old man exhibited confluent drusen in the right eye beneath the fovea. During regular follow-up, an eccentric full-thickness macular hole developed in the right eye and closed spontaneously. Concurrently, the confluent drusen showed rapid regression without signs of geographic atrophy or macular neovascularization. Visual acuity remained stable throughout the monitoring period.</p><p><strong>Conclusion: </strong>This case suggests that drusen regression can occur alongside spontaneous full-thickness macular hole closure without surgical intervention. This adds to the current understanding of the pathology and treatment of drusen.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"701-704"},"PeriodicalIF":0.0000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Retinal Cases and Brief Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ICB.0000000000001658","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
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Abstract
Purpose: The objective of this study was to describe a unique case of drusen resolution accompanying the spontaneous closure of an eccentric full-thickness macular hole.
Methods: This study is a case report.
Results: A 71-year-old man exhibited confluent drusen in the right eye beneath the fovea. During regular follow-up, an eccentric full-thickness macular hole developed in the right eye and closed spontaneously. Concurrently, the confluent drusen showed rapid regression without signs of geographic atrophy or macular neovascularization. Visual acuity remained stable throughout the monitoring period.
Conclusion: This case suggests that drusen regression can occur alongside spontaneous full-thickness macular hole closure without surgical intervention. This adds to the current understanding of the pathology and treatment of drusen.
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