Prediction of refraction error after toric lens implantation with biometric input data uncertainties and power labelling tolerances.

IF 4.9 2区医学 Q1 OPHTHALMOLOGY Clinical and Experimental Ophthalmology Pub Date : 2024-10-09 DOI:10.1111/ceo.14449

Achim Langenbucher, Nóra Szentmáry, Alan Cayless, David Cooke, Peter Hoffmann, Jascha Wendelstein

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Abstract

Background: The purpose of this study was to simulate the impact of biometric measure uncertainties, lens equivalent and toric power labelling tolerances and axis alignment errors on the refractive outcome after cataract surgery with toric lens implantation.

Methods: In this retrospective non-randomised cross sectional Monte-Carlo simulation study we evaluated a dataset containing 7458 LenStar 900 preoperative biometric measurements. The biometric uncertainties from literature, lens power labelling according to ISO 11979, and axis alignment tolerances of a modern toric lens (Hoya Vivinex) were taken to be normally distributed and used in a Monte-Carlo simulation with 100 000 samples per eye. The target variable was the defocus equivalent (DEQ) derived using the Castrop (DEQ_C) and the Haigis (DEQ_H) formulae.

Results: Mean/median / 90% quantile DEQ_C was 0.22/0.21/0.36 D and DEQ_H was 0.20/0.19/0.32 D. Ignoring the variation in lens power labelling and toric axis alignment the respective DEQ_C was 0.20/0.19/0.32 D and DEQ_H was 0.18/0.17/0.29 D. DEQ_C and DEQ_H increased with shorter eyes, steeper corneas, equivalent lens power and highly with toric lens power.

Conclusions: According to our simulation results, uncertainties in biometric measures, lens power labelling tolerances, and axis alignment errors are responsible for a significant part of the refraction prediction error after cataract surgery with toric lens implantation. Additional labelling of the exact equivalent and toric power on the lens package could be a step to improve postoperative results.

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利用生物统计学输入数据的不确定性和功率标签公差，预测散光晶体植入术后的屈光误差。

背景：本研究的目的是模拟生物测量不确定性、晶状体等效和散光功率标注公差以及轴对准误差对散光晶状体植入白内障手术后屈光结果的影响：在这项回顾性非随机横断面蒙特卡洛模拟研究中，我们评估了包含 7458 个 LenStar 900 术前生物测量数据集。文献中的生物测量不确定性、根据 ISO 11979 进行的镜片功率标注以及现代散光透镜（Hoya Vivinex）的轴对准公差均被视为正态分布，并用于每只眼睛 100 000 个样本的蒙特卡洛模拟。目标变量是使用卡斯特罗普（DEQC）和海吉斯（DEQH）公式得出的散焦当量（DEQ）：平均值/中值/90%量值 DEQC 为 0.22/0.21/0.36 D，DEQH 为 0.20/0.19/0.32 D。如果忽略镜片功率标记和散光轴对准的变化，DEQC分别为0.20/0.19/0.32 D，DEQH分别为0.18/0.17/0.29 D。DEQC和DEQH随着眼球变短、角膜变陡和等效镜片功率的增加而增加，随着散光镜片功率的增加而增加：根据我们的模拟结果，生物测量的不确定性、镜片功率标注公差和轴对齐误差是造成散光人工晶体植入白内障手术后屈光度预测误差的主要原因。在镜片包装上额外标注精确的等效和散光功率可能是改善术后效果的一个步骤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Ophthalmology 医学-眼科学

CiteScore

7.60

自引率

12.50%

发文量

150

审稿时长

4-8 weeks

期刊介绍： Clinical & Experimental Ophthalmology is the official journal of The Royal Australian and New Zealand College of Ophthalmologists. The journal publishes peer-reviewed original research and reviews dealing with all aspects of clinical practice and research which are international in scope and application. CEO recognises the importance of collaborative research and welcomes papers that have a direct influence on ophthalmic practice but are not unique to ophthalmology.