[Amyloidosis].

Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-10-01 Epub Date: 2024-10-09 DOI:10.1055/a-2278-7742
Ute Hegenbart, Kiavasch M N Farid, Stefan Schönland
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Abstract

Amyloidosis are rare protein misfolding and deposition diseases which, with very few exceptions, are treatable easily nowadays. The prognosis depends on the form of amyloidosis, which is particularly unfavorable for heart involvement that is diagnosed too late. Patients die within months to a few years or suffer irreversible loss of function of the affected organs. Once the diagnosis has been made, treatment should be started without delay. Amyloidosis centers offer support in the diagnosis and development as well as clinical trials of an optimal therapy concept.

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[淀粉样变性]
淀粉样变性是一种罕见的蛋白质错误折叠和沉积疾病,除了极少数例外,如今都很容易治疗。预后取决于淀粉样变性的形式,尤其是对诊断太晚的心脏受累患者不利。患者会在数月至数年内死亡,或受累器官不可逆转地丧失功能。一旦确诊,应立即开始治疗。淀粉样变性中心在诊断、开发和临床试验最佳治疗方案方面提供支持。
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