Correction: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner

Abstract

Molecular Neurodegeneration (2024) 19:18

https://doi.org/10.1186/s13024-023-00700-w

The original article erroneously presents incorrect graph labels in the caption of Fig. 4. The corrected Fig. 4 caption alongside its respective figure can be viewed ahead in this Correction article.

Fig. 4

GV-971 modifies cytokine and chemokine levels in peripheral blood and cortical tissues. (a) Quantification of cytokine and chemokine concentrations in the serum of APPPS1-21 male mice treated with 160mg/kg GV-971 or vehicle from the University of Chicago (n = 10–11). (b) Quantification of cytokine and chemokine concentrations in the serum of APPPS1-21 female mice treated with 160mg/kg GV-971 or vehicle (n = 8–10). (c) Quantification of cytokine and chemokine concentrations in the serum of 5XFAD male mice treated with 100mg/kg GV-971 or vehicle from Washington University in St. Louis (n = 12–13). (d) Quantification of cytokine and chemokine concentrations in the serum of 5XFAD female mice treated with 100mg/kg GV-971 or vehicle (n = 9–12). (e) Quantification of cytokine and chemokine concentrations in the cortical tissue of 5XFAD male mice treated with 100mg/kg GV-971 or vehicle (n = 12–13). Data presented as SEM. Significance determined using unpaired t-test. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001

Full size image

Author notes

1. Megan E. Bosch and Hemraj B. Dodiya contributed equally to this work.

2. Julia Michalkiewicz, Choonghee Lee and Shabana M. Shaik contributed equally to this work.

Authors and Affiliations

1. Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer’s Disease Research Center, Washington University in St. Louis, St. Louis, USA

   Megan E. Bosch, Choonghee Lee, Aishwarya Nambiar, Samira Parhizkar & David M. Holtzman

2. Department of Neurobiology, University of Chicago, Chicago, USA

   Hemraj B. Dodiya, Julia Michalkiewicz, Shabana M. Shaik, Ian Q. Weigle, Jack Osborn, Xiaoqiong Zhang & Sangram S. Sisodia

3. Genetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

   Can Zhang, Prasenjit Mondal, Ashley Gomm & Rudolph E. Tanzi

4. Center for Genetic Medicine, Northwestern University, Chicago, USA

   Priyam Patel & Matthew John Schipma

5. Genome Technology Access Center, Washington University in St. Louis, St. Louis, USA

   Marie L. Laury

6. Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

   Dania Mallah & Oleg Butovsky

7. Department Medicine, Section of Gastroenterology, Hepatology, and Nutrition, The University of Chicago, Chicago, USA

   Eugene B. Chang

8. Department of Pediatrics and Scripps Institution of Oceanography, UCSD, San Diego, USA

   Jack A. Gilbert

Authors

1. Megan E. BoschView author publications

   You can also search for this author in PubMed Google Scholar

2. Hemraj B. DodiyaView author publications

   You can also search for this author in PubMed Google Scholar

3. Julia MichalkiewiczView author publications

   You can also search for this author in PubMed Google Scholar

4. Choonghee LeeView author publications

   You can also search for this author in PubMed Google Scholar

5. Shabana M. ShaikView author publications

   You can also search for this author in PubMed Google Scholar

6. Ian Q. WeigleView author publications

   You can also search for this author in PubMed Google Scholar

7. Can ZhangView author publications

   You can also search for this author in PubMed Google Scholar

8. Jack OsbornView author publications

   You can also search for this author in PubMed Google Scholar

9. Aishwarya NambiarView author publications

   You can also search for this author in PubMed Google Scholar

10. Priyam PatelView author publications

    You can also search for this author in PubMed Google Scholar

11. Samira ParhizkarView author publications

    You can also search for this author in PubMed Google Scholar

12. Xiaoqiong ZhangView author publications

    You can also search for this author in PubMed Google Scholar

13. Marie L. LauryView author publications

    You can also search for this author in PubMed Google Scholar

14. Prasenjit MondalView author publications

    You can also search for this author in PubMed Google Scholar

15. Ashley GommView author publications

    You can also search for this author in PubMed Google Scholar

16. Matthew John SchipmaView author publications

    You can also search for this author in PubMed Google Scholar

17. Dania MallahView author publications

    You can also search for this author in PubMed Google Scholar

18. Oleg ButovskyView author publications

    You can also search for this author in PubMed Google Scholar

19. Eugene B. ChangView author publications

    You can also search for this author in PubMed Google Scholar

20. Rudolph E. TanziView author publications

    You can also search for this author in PubMed Google Scholar

21. Jack A. GilbertView author publications

    You can also search for this author in PubMed Google Scholar

22. David M. HoltzmanView author publications

    You can also search for this author in PubMed Google Scholar

23. Sangram S. SisodiaView author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to David M. Holtzman or Sangram S. Sisodia.

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The online version of the original article can be found at https://doi.org/10.1186/s13024-023-00700-w.

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

Cite this article

Bosch, M.E., Dodiya, H.B., Michalkiewicz, J. et al. Correction: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Mol Neurodegeneration 19, 70 (2024). https://doi.org/10.1186/s13024-024-00764-2

Download citation

• Published: 10 October 2024

• DOI: https://doi.org/10.1186/s13024-024-00764-2

Share this article

Anyone you share the following link with will be able to read this content:

Get shareable link

Sorry, a shareable link is not currently available for this article.

Copy to clipboard

Provided by the Springer Nature SharedIt content-sharing initiative