A suprapubic refractory skin ulcer following keloid radiotherapy: from hyper-proliferation to hypo-proliferation.

IF 1.5 4区医学 Q3 DERMATOLOGY Journal of wound care Pub Date : 2024-10-01 DOI:10.12968/jowc.2021.0314

Renpeng Zhou, Jialin Hou, Xiujun Fu, Chen Wang, Yimin Liang, Danru Wang

引用次数: 0

Abstract

Radiation-induced skin ulcer following cancer and/or tumour is well-documented in the literature. However, radiation-induced skin ulcer following the excision of keloid is yet to be reported. Here, we report the case of a 33-year-old female patient with a suprapubic skin ulcer of five months' duration following keloid treatment with electron beam therapy at recommended dosage. Various examinations, including a skin biopsy, metagenomic sequencing, magnetic resonance imaging and immunochemistry, indicated that the skin ulcer was induced by radiotherapy. While postoperative radiotherapy has been recommended immediately following keloid excision to reduce the risk of recurrence, the present case highlights the risk of skin refractory ulcer following keloid radiotherapy.

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瘢痕疙瘩放疗后的耻骨上难治性皮肤溃疡：从过度增殖到过度增殖。

癌症和/或肿瘤引起的辐射诱发皮肤溃疡在文献中已有大量记载。然而，瘢痕疙瘩切除术后辐射诱发的皮肤溃疡尚未见报道。在此，我们报告了一例 33 岁女性患者的病例，该患者在使用推荐剂量的电子束治疗瘢痕疙瘩后，出现了持续 5 个月的耻骨上皮肤溃疡。包括皮肤活检、元基因组测序、磁共振成像和免疫化学在内的各种检查结果表明，皮肤溃疡是由放疗诱发的。虽然建议在瘢痕疙瘩切除术后立即进行术后放疗以降低复发风险，但本病例凸显了瘢痕疙瘩放疗后出现皮肤难治性溃疡的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.