Sexual function and fertility in young female adults surgically treated for anorectal malformations.

IF 1.5 3区 医学 Q2 PEDIATRICS Pediatric Surgery International Pub Date : 2024-10-10 DOI:10.1007/s00383-024-05847-1
Joshua Gertler, Jenny Oddsberg, Anna Gunnarsdóttir, Anna Svenningsson, Tomas Wester, Lisa Örtqvist
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Abstract

Purpose: The aim was to investigate sexual function and fertility in female adults operated on for anorectal malformations (ARM).

Methods: This was a cross-sectional questionnaire-based study including female adult patients treated for ARM at our institution between 1994 and 2003. Sexual function in females was assessed using the Profile of Sexual Function (PFSF). Additional questions regarding fertility were answered by the participants. Patient characteristics were retrospectively retrieved from the medical records and descriptive statistics were used for analysis. Sexual function outcomes were compared to a control group from a previously published group of females. Composite outcome analysis was performed using previously published data to determine the potential impact of bowel function and health-related quality of life on sexual function. The ethics review authorities approved the study.

Results: A total of 14 of 30 (46.7%) females responded to the questionnaires and had a mean age of 21.1 years (range 18-26). No association was found between PFSF and age or bowel function (Bowel Function Score), however, a strong correlation was found between PFSF and health-related quality of life (HRQoL) with a Spearman correlation of ρ 0.82 (p = 0.0011). The general satisfaction question was strongly associated with their total PFSF score (ρ = 0.71, p = 0.0092). Except for the "desire" item, the females in this cohort did not have significantly worse sexual function than the control population(p = 0.015). Ten of fourteen (71.4%) females had had their sexual debut at a mean age of 16.3 years and two of these women (20%) have been pregnant. All females had had menarche at a mean age of 12.7 years.

Conclusion: Sexual function in adult females was comparable to healthy controls except for the "desire" item where the cohort reported poorer outcomes. The cohort's sexual function had a direct association with their reported HRQoL where individuals with worse HRQoL also reported poorer sexual function.

Level of evidence: III.

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接受肛门直肠畸形手术治疗的年轻女性的性功能和生育能力。
目的:旨在调查因肛门直肠畸形(ARM)而接受手术的成年女性的性功能和生育能力:这是一项基于问卷调查的横断面研究,研究对象包括 1994 年至 2003 年期间在我院接受过肛门直肠畸形手术治疗的成年女性患者。女性的性功能通过性功能档案(PFSF)进行评估。参与者还回答了有关生育的其他问题。从病历中回顾性地提取了患者的特征,并使用描述性统计进行分析。性功能结果与之前发表的一组女性对照组进行了比较。利用之前发表的数据进行了综合结果分析,以确定肠道功能和健康相关生活质量对性功能的潜在影响。伦理审查机构批准了这项研究:30名女性中共有14人(46.7%)回答了问卷,平均年龄为21.1岁(18-26岁不等)。未发现 PFSF 与年龄或肠道功能(肠道功能评分)之间存在关联,但发现 PFSF 与健康相关生活质量(HRQoL)之间存在很强的相关性,Spearman 相关性为 ρ 0.82 (p = 0.0011)。一般满意度问题与 PFSF 总分密切相关(ρ = 0.71,p = 0.0092)。除 "欲望 "一项外,该组女性的性功能并没有明显差于对照组(p = 0.015)。14 名女性中有 10 名(71.4%)在平均 16.3 岁时初次性行为,其中有两名女性(20%)已经怀孕。所有女性月经初潮的平均年龄为 12.7 岁:结论:成年女性的性功能与健康对照组相当,但在 "欲望 "一项上,该组女性的结果较差。人群的性功能与其报告的 HRQoL 有直接关系,HRQoL 较差的人报告的性功能也较差:证据等级:III。
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来源期刊
CiteScore
3.00
自引率
5.60%
发文量
215
审稿时长
3-6 weeks
期刊介绍: Pediatric Surgery International is a journal devoted to the publication of new and important information from the entire spectrum of pediatric surgery. The major purpose of the journal is to promote postgraduate training and further education in the surgery of infants and children. The contents will include articles in clinical and experimental surgery, as well as related fields. One section of each issue is devoted to a special topic, with invited contributions from recognized authorities. Other sections will include: -Review articles- Original articles- Technical innovations- Letters to the editor
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