Multifarious Aspect of Cytokines as an Immuno-Therapeutic for Various Diseases.

IF 1.9 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Interferon and Cytokine Research Pub Date : 2024-11-01 Epub Date: 2024-10-11 DOI:10.1089/jir.2024.0090
Yash Sharma, Kumud Bala
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Abstract

Cytokines are known to be a group of growing small proteins that are majorly responsible for the transmission of signals and communication between hematopoietic cells, the cells of the human immune system, and other types of cells. Cytokines play a dominant role in different types of disorders and in perpetuating the inflammation-related disorders. The production of cytokines is a natural process inside the body of a human being against any foreign invasion or due to some pathogenic state to maintain the homeostasis. Cytokines respond in two ways; in some cases, the production and development of cytokines as a therapeutic discovery or intervention will enhance the treatment process and support the reaction given by the body against any pathogenic activity, and in some cases, overproduction of these cytokines responds in the opposite way and behaves as antagonists toward a typical therapeutic drug and its treatment. Overall, 41 articles were reviewed, and it was found that cytokines have proved to be a therapeutic approach among various diseases and can be utilized as a good candidate or a better choice for cancer therapeutics in future development.

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细胞因子作为各种疾病免疫疗法的多面性。
众所周知,细胞因子是一组不断生长的小蛋白,主要负责造血细胞、人体免疫系统细胞和其他类型细胞之间的信号传递和交流。细胞因子在不同类型的疾病和炎症相关疾病的持续存在中发挥着主导作用。细胞因子的产生是人体内抵抗外来入侵或由于某种致病状态而维持体内平衡的一个自然过程。细胞因子有两种反应方式:在某些情况下,细胞因子的产生和发展作为一种治疗发现或干预措施,会加强治疗过程并支持机体对任何致病活动的反应;而在某些情况下,这些细胞因子的过度产生则会以相反的方式作出反应,并对典型的治疗药物及其疗法产生拮抗作用。通过对 41 篇文章的综述,我们发现细胞因子已被证明是治疗各种疾病的一种方法,在未来的发展中,细胞因子可被用作癌症治疗的候选药物或更好的选择。
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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
78
审稿时长
2.2 months
期刊介绍: Journal of Interferon & Cytokine Research (JICR) provides the latest groundbreaking research on all aspects of IFNs and cytokines. The Journal delivers current findings on emerging topics in this niche community, including the role of IFNs in the therapy of diseases such as multiple sclerosis, the understanding of the third class of IFNs, and the identification and function of IFN-inducible genes.
期刊最新文献
Dual Time-Dependent Effects of Interleukin-33 Administration on the Kidney Postmyocardial Infarction. Integrated Analysis of Noncoding RNAs (PVT-1 and miR-200c) and Their Correlation with STAT4/IL-6 Axis as Reliable Biomarkers for COVID-19 Severity. IL-4 Downregulates PD-L1 Level Via SOCS1 Upregulation-Induced JNK Deactivation to Enhance Antitumor Immunity in In Vitro Colorectal Cancer. Multifarious Aspect of Cytokines as an Immuno-Therapeutic for Various Diseases. The Impact of Chemokine-Like Receptor 1 Gene Knockout on Lipopolysaccharide-Induced Epididymo-Orchitis in Mice.
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