Visible-light-induced dual CH functionalization of biaryl ynones via a 6-exo-trig domino radical addition/cyclization/dearomatization: Efficient access to alkylated spiro[5.5] trienones
{"title":"Visible-light-induced dual CH functionalization of biaryl ynones via a 6-exo-trig domino radical addition/cyclization/dearomatization: Efficient access to alkylated spiro[5.5] trienones","authors":"","doi":"10.1016/j.tetlet.2024.155312","DOIUrl":null,"url":null,"abstract":"<div><div>A visible-light-induced 6-exo-trig tandem cyclization dearomatization of biaryl ynones with simple ethers was developed. The reaction involves selective C(sp<sup>3</sup>)<img>H bond cleavage and dual C<img>C bond formation providing efficient, atom and step economical access to alkylated spiro[5.5]trienones under mild conditions.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040403924004076","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A visible-light-induced 6-exo-trig tandem cyclization dearomatization of biaryl ynones with simple ethers was developed. The reaction involves selective C(sp3)H bond cleavage and dual CC bond formation providing efficient, atom and step economical access to alkylated spiro[5.5]trienones under mild conditions.
期刊介绍:
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.