Recent advances in electrochemical biosensors for the detection of pathogens, diseases biomarkers, and heavy metal ions

IF 2.7 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR Inorganica Chimica Acta Pub Date : 2024-10-09 DOI:10.1016/j.ica.2024.122403

Manoj Kumar Goshisht , Goutam Kumar Patra , Aabroo Mahal , Ajaya Kumar Singh , Shobha , Mahavir Parshad

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Abstract

The excessive usage of chemicals has resulted in environmental pollution worldwide leading to several health issues. The continuous rise in multidrug-resistance (MDR) pathogens is further challenging global health. The detection of these harmful chemicals, pathogens, and disease biomarkers is essential to combat these challenges. In this review, we describe different electrochemical biosensors to detect pathogens, disease biomarkers, and heavy metal ions (HMIs). The review has been devised in three parts. The first part involves discussion of different types of electrochemical biosensors for detecting MDR pathogens along with their mechanism of detection. The second part involves detection and monitoring of diabetes mellitus, cancer, and neurodegenerative diseases. The third part sheds light on the detection of heavy metal ions and monitoring of the environment. This review article has covered the literature based on different types of electrochemical biosensor, their working principles, mechanisms, and applications in detection of disease biomarkers, pathogens, and HMIs from 2017 to 2023.

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用于检测病原体、疾病生物标记物和重金属离子的电化学生物传感器的最新进展

化学品的过度使用造成了全球范围内的环境污染，导致了多种健康问题。多重耐药性（MDR）病原体的不断增加进一步挑战着全球健康。检测这些有害化学物质、病原体和疾病生物标志物对于应对这些挑战至关重要。在本综述中，我们介绍了用于检测病原体、疾病生物标志物和重金属离子 (HMI) 的各种电化学生物传感器。综述分为三个部分。第一部分讨论了用于检测 MDR 病原体的不同类型的电化学生物传感器及其检测机制。第二部分涉及糖尿病、癌症和神经退行性疾病的检测和监测。第三部分阐述了重金属离子的检测和环境监测。这篇综述文章涵盖了从 2017 年到 2023 年基于不同类型电化学生物传感器、其工作原理、机制以及在疾病生物标志物、病原体和 HMIs 检测中的应用的文献。

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来源期刊

Inorganica Chimica Acta 化学-无机化学与核化学

CiteScore

6.00

自引率

3.60%

发文量

440

审稿时长

35 days

期刊介绍： Inorganica Chimica Acta is an established international forum for all aspects of advanced Inorganic Chemistry. Original papers of high scientific level and interest are published in the form of Articles and Reviews. Topics covered include: • chemistry of the main group elements and the d- and f-block metals, including the synthesis, characterization and reactivity of coordination, organometallic, biomimetic, supramolecular coordination compounds, including associated computational studies; • synthesis, physico-chemical properties, applications of molecule-based nano-scaled clusters and nanomaterials designed using the principles of coordination chemistry, as well as coordination polymers (CPs), metal-organic frameworks (MOFs), metal-organic polyhedra (MPOs); • reaction mechanisms and physico-chemical investigations computational studies of metalloenzymes and their models; • applications of inorganic compounds, metallodrugs and molecule-based materials. Papers composed primarily of structural reports will typically not be considered for publication.

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