Comparative analysis of phytochemical constituents in different parts of Aspilia africana: A potential medicinal plant for therapeutic applications

Q3 Pharmacology, Toxicology and Pharmaceutics Phytomedicine Plus Pub Date : 2024-10-09 DOI:10.1016/j.phyplu.2024.100656
Gerheart Winfred Ashong, Edward Ebow Kwaansa – Ansah, Mohammed Alhassan, Prince Nana Adofo, Jeremiah Adu Sarkodie, Boansi Adu Ababio
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Abstract

Background

Among the diverse array of plants used in traditional medicine, Aspilia africana is highly valued due to its high efficacy against many ailments and its well-noted potential for wound healing. The plant has been widely used to cure illnesses in traditional medicine, which is practiced throughout much of Africa, where an estimated about 80 % of the population gets their main healthcare from this source.

Purpose

This study aimed to qualitatively screen the phytochemical constituents of Aspilia africana to confirm its therapeutic properties and generate scientific proof that justifies its usage in traditional medicine.

Study design

Aspilia africana stem, roots, and leaves were screened qualitatively for phytochemical components using pet-ether extracts and distilled water, and qualitative data was generated.

Method

Extraction of phytochemicals was done by using the cold maceration method, 150 g of each of the dried parts were taken and packed into 3 separate glass jars containing 500 ml of each solvent (distilled water and pet-ether solvents) and allowed to stand for 24 h.

Results

This study found 15 phytochemicals which include tannins, phlobatannins, alkaloids, terpenoids, flavonols, glycosides, phenols, steroids, anthraquinones, saponins, phytosterols, proteins and amino acids, coumarins, cardiac glycosides, and flavonoids in A. africana. The occurrence of the therapeutic components in the aqueous extract of roots, leaves, and stem were nine (9), nine (9), and eight (8) respectively, and that of the pet-ether extract were nine (9), eight (8), and seven (7) in roots, leaves, and stem respectively.

Conclusion

The presence of these phytochemicals indicates prospective uses in the pharmaceutical and nutraceutical industries, as well as supports the use of Aspilia africana in traditional medicine. To completely understand and make use of the plant's medicinal qualities, further investigations are required on its anti-microbial activities.

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Aspilia africana 不同部位植物化学成分的比较分析:一种具有治疗用途的潜在药用植物
背景在传统医学中使用的各种植物中,非洲罂粟因其对多种疾病的高效疗效和广为人知的伤口愈合潜力而备受推崇。本研究旨在定性筛选非洲穗花的植物化学成分,以确认其治疗特性,并为其在传统医学中的应用提供科学依据。研究设计使用石油醚提取物和蒸馏水定性筛选非洲穗花的茎、根和叶的植物化学成分,并生成定性数据。方法植物化学成分的萃取采用冷浸渍法,每种干燥部分各取 150 克,分别装入 3 个玻璃瓶中,每个瓶中分别装有 500 毫升溶剂(蒸馏水和石油醚溶剂),放置 24 小时。结果这项研究在非洲杉中发现了 15 种植物化学物质,包括单宁、磷脂单宁、生物碱、萜类、黄酮醇、苷类、酚类、甾体、蒽醌类、皂苷、植物甾醇、蛋白质和氨基酸、香豆素、强心苷和黄酮类。在根、叶和茎的水提取物中,治疗成分的出现率分别为 9(9)、9(9)和 8(8);在根、叶和茎的乙醚提取物中,治疗成分的出现率分别为 9(9)、8(8)和 7(7)。要完全了解和利用该植物的药用价值,还需要进一步研究其抗微生物活性。
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来源期刊
Phytomedicine Plus
Phytomedicine Plus Medicine-Complementary and Alternative Medicine
CiteScore
3.70
自引率
0.00%
发文量
178
审稿时长
81 days
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