Michael M. Wade Wolfe, Jonathan E. Pines, Andrew R. Sosa, Michael D. Pluth
{"title":"Exploring the Reactivity of Electrophilic Organic Carbonates and Thiocarbonates as Vehicles to Convert Hydrosulfide into COS and CS2","authors":"Michael M. Wade Wolfe, Jonathan E. Pines, Andrew R. Sosa, Michael D. Pluth","doi":"10.1021/acs.joc.4c01690","DOIUrl":null,"url":null,"abstract":"Hydrogen sulfide (H<sub>2</sub>S) and other reactive sulfur species are important small molecules with biological significance. In addition to common reactive sulfur species like H<sub>2</sub>S, polysulfides, and persulfides, both carbonyl sulfide (COS) and carbon disulfide (CS<sub>2</sub>) have been postulated to be potential sources of reduced sulfur. To better understand this possible connection, we demonstrate that H<sub>2</sub>S can be converted to COS and CS<sub>2</sub> by reaction with simple organic carbonate and thiocarbonate electrophiles, respectively.","PeriodicalId":57,"journal":{"name":"The Journal of Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Organic Chemistry","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1021/acs.joc.4c01690","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Hydrogen sulfide (H2S) and other reactive sulfur species are important small molecules with biological significance. In addition to common reactive sulfur species like H2S, polysulfides, and persulfides, both carbonyl sulfide (COS) and carbon disulfide (CS2) have been postulated to be potential sources of reduced sulfur. To better understand this possible connection, we demonstrate that H2S can be converted to COS and CS2 by reaction with simple organic carbonate and thiocarbonate electrophiles, respectively.
期刊介绍：
The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
