{"title":"Metal Free Visible-Light-Induced Borylative/Silylative Pyridylation of Vinylarenes","authors":"Yiting Zhou, Bin Liu","doi":"10.1039/d4qo01702a","DOIUrl":null,"url":null,"abstract":"We present a metal-free and gentle three-component reaction involving vinylarenes, NHC-BH3 complexes, hydrosilanes, and 4-cyanopyridine. This versatile reaction encompasses a broad scope, encompassing over 40 examples of vinylarenes, NHC-BH3 complexes, and hydrosilanes, leading to the synthesis of diverse β-pyridinyl boranes and β-pyridinyl silanes. Furthermore, we demonstrate the potential of this methodology by functionalizing pharmaceutical molecules, showcasing its practical applications","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4qo01702a","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
We present a metal-free and gentle three-component reaction involving vinylarenes, NHC-BH3 complexes, hydrosilanes, and 4-cyanopyridine. This versatile reaction encompasses a broad scope, encompassing over 40 examples of vinylarenes, NHC-BH3 complexes, and hydrosilanes, leading to the synthesis of diverse β-pyridinyl boranes and β-pyridinyl silanes. Furthermore, we demonstrate the potential of this methodology by functionalizing pharmaceutical molecules, showcasing its practical applications
期刊介绍：
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.
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