Glucose metrics and device satisfaction in adults with type 1 diabetes using different treatment modalities: a multicenter, real-world observational study.

IF 3.1 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Acta Diabetologica Pub Date : 2024-10-10 DOI:10.1007/s00592-024-02381-3
S Di Molfetta, A Rossi, R Gesuita, A Faragalli, A Cutruzzolà, C Irace, N Minuto, D Pitocco, F Cardella, C Arnaldi, A Frongia, E Mozzillo, B Predieri, P Fiorina, F Giorgino, V Cherubini
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Abstract

Aims: To evaluate glucose metrics, device satisfaction and diabetes impact in adults with type 1 diabetes using different treatment modalities in a real-life setting in Italy.

Methods: This was a multicentre, nationwide, cross-sectional study. Candidates were consecutively evaluated for eligibility during their routine medical visit at the diabetes centre. Researchers collected comprehensive demographic, socioeconomic, anamnestic and clinical data, and administered the Diabetes Impact and Device Satisfaction scale.

Results: From 2021 to 2022, a total of 428 subjects, 45% males, with a median age of 32 years (IQR 23-47) were recruited in 11 participating centres from all over Italy. No differences in age, physical activity, and diabetes impact were found for the different treatment modalities. HCL/AHCL and SAP groups reported higher device satisfaction vs. MDI + SMBG and MDI + CGM (p < 0.001). Subjects treated with HCL/AHCL exhibited significantly higher TIR and significantly lower time spent in hypoglycemia level 1, time spent in hyperglycemia, CV and GMI compared to MDI + CGM, and significantly higher TIR and significantly lower time spent in hypoglycemia level 2, time spent in hyperglycemia, and CV compared to SAP. Significant reduction in hypoglycemia level 2 was also found with PLGM compared to SAP. High education attainment was associated with optimal metabolic control.

Conclusion: Real-life use of advanced technologies for type 1 diabetes is associated with improved glucose metrics and device satisfaction. Education level also contributes to success of treatment.

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使用不同治疗模式的成人 1 型糖尿病患者的血糖指标和设备满意度:一项多中心、真实世界观察研究。
目的:在意大利的真实环境中,评估使用不同治疗模式的 1 型糖尿病成人患者的血糖指标、设备满意度和对糖尿病的影响:这是一项多中心、全国性的横断面研究。候选者在糖尿病中心接受例行体检时连续接受资格评估。研究人员收集了全面的人口统计学、社会经济学、解剖学和临床数据,并实施了糖尿病影响和设备满意度量表:从 2021 年到 2022 年,意大利全国 11 个参与中心共招募了 428 名受试者,其中 45% 为男性,中位年龄为 32 岁(IQR 23-47)。不同的治疗模式在年龄、体力活动和糖尿病影响方面均无差异。与 MDI + SMBG 和 MDI + CGM 相比,HCL/AHCL 组和 SAP 组的设备满意度更高(p 结论:HCL/AHCL 组和 SAP 组的设备满意度高于 MDI + SMBG 组和 MDI + CGM 组):在实际生活中使用先进技术治疗 1 型糖尿病与血糖指标和设备满意度的改善有关。教育水平也有助于治疗的成功。
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来源期刊
Acta Diabetologica
Acta Diabetologica 医学-内分泌学与代谢
CiteScore
7.30
自引率
2.60%
发文量
180
审稿时长
2 months
期刊介绍: Acta Diabetologica is a journal that publishes reports of experimental and clinical research on diabetes mellitus and related metabolic diseases. Original contributions on biochemical, physiological, pathophysiological and clinical aspects of research on diabetes and metabolic diseases are welcome. Reports are published in the form of original articles, short communications and letters to the editor. Invited reviews and editorials are also published. A Methodology forum, which publishes contributions on methodological aspects of diabetes in vivo and in vitro, is also available. The Editor-in-chief will be pleased to consider articles describing new techniques (e.g., new transplantation methods, metabolic models), of innovative importance in the field of diabetes/metabolism. Finally, workshop reports are also welcome in Acta Diabetologica.
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