Cartilage Tissue Engineering in Multilayer Tissue Regeneration.

IF 3 2区 医学 Q3 ENGINEERING, BIOMEDICAL Annals of Biomedical Engineering Pub Date : 2024-10-14 DOI:10.1007/s10439-024-03626-6
Hilal Yilmaz, Israa F Abdulazez, Sevda Gursoy, Yagmur Kazancioglu, Cem Bulent Ustundag
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Abstract

The functional and structural integrity of the tissue/organ can be compromised in multilayer reconstructive applications involving cartilage tissue. Therefore, multilayer structures are needed for cartilage applications. In this review, we have examined multilayer scaffolds for use in the treatment of damage to organs such as the trachea, joint, nose, and ear, including the multilayer cartilage structure, but we have generally seen that they have potential applications in trachea and joint regeneration. In conclusion, when the existing studies are examined, the results are promising for the trachea and joint connections, but are still limited for the nasal and ear. It may have promising implications in the future in terms of reducing the invasiveness of existing grafting techniques used in the reconstruction of tissues with multilayered layers.

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多层组织再生中的软骨组织工程。
在涉及软骨组织的多层重建应用中,组织/器官的功能和结构完整性可能会受到影响。因此,软骨应用需要多层结构。在本综述中,我们研究了用于治疗气管、关节、鼻和耳等器官损伤的多层支架,包括多层软骨结构,但我们普遍认为它们在气管和关节再生方面具有潜在的应用价值。总之,从现有的研究来看,气管和关节连接方面的研究结果令人鼓舞,但鼻腔和耳部的研究结果仍然有限。未来,在减少用于多层组织重建的现有移植技术的侵入性方面,它可能会有很好的应用前景。
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来源期刊
Annals of Biomedical Engineering
Annals of Biomedical Engineering 工程技术-工程:生物医学
CiteScore
7.50
自引率
15.80%
发文量
212
审稿时长
3 months
期刊介绍: Annals of Biomedical Engineering is an official journal of the Biomedical Engineering Society, publishing original articles in the major fields of bioengineering and biomedical engineering. The Annals is an interdisciplinary and international journal with the aim to highlight integrated approaches to the solutions of biological and biomedical problems.
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