Current and Emerging Radiotracers in Molecular Cardiovascular Imaging.

IF 6.5 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Circulation: Cardiovascular Imaging Pub Date : 2024-10-01 Epub Date: 2024-10-15 DOI:10.1161/CIRCIMAGING.123.016323
Shruti S Joshi, Jolien Geers, Alessia Gimelli, Fabien Hyafil, Gilbert Habib, Paola Erba, Olivier Gheysens, Andor W J M Glaudemans, David E Newby, Riemer H J A Slart, Marc R Dweck
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Abstract

Cardiovascular imaging has rapidly advanced over the past decades. Traditional imaging techniques such as echocardiography, computed tomography, and cardiovascular magnetic resonance are essential for assessing the structural and functional aspects of the cardiovascular system but often fall short in providing direct insights into disease activity. This gap is increasingly being bridged by molecular nuclear imaging techniques, including positron emission tomography and single-photon emission computed tomography, which enable the visualization of disease processes at the molecular and cellular levels. This review highlights the role of cardiovascular molecular imaging, emphasizing its current and potential applications in diagnosing and managing cardiovascular disease. With advancements in positron emission tomography scanners, novel radiotracers, and sophisticated imaging software, molecular imaging is set to play an essential role in precision medicine by enhancing our understanding of disease mechanisms, accelerating the development of targeted therapies, and facilitating personalized patient care.

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分子心血管成像中当前和新兴的放射性核素。
过去几十年来,心血管成像技术发展迅速。超声心动图、计算机断层扫描和心血管磁共振等传统成像技术对于评估心血管系统的结构和功能至关重要,但往往无法直接了解疾病的活动情况。分子核成像技术(包括正电子发射计算机断层扫描和单光子发射计算机断层扫描)越来越多地弥补了这一不足,使疾病过程在分子和细胞水平上可视化。这篇综述突出了心血管分子成像的作用,强调了其在诊断和管理心血管疾病方面的当前和潜在应用。随着正电子发射断层扫描仪、新型放射性racracers 和先进成像软件的发展,分子成像技术将在精准医疗中发挥重要作用,增强我们对疾病机制的了解,加快靶向疗法的开发,促进个性化患者护理。
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来源期刊
CiteScore
6.30
自引率
2.70%
发文量
225
审稿时长
6-12 weeks
期刊介绍: Circulation: Cardiovascular Imaging, an American Heart Association journal, publishes high-quality, patient-centric articles focusing on observational studies, clinical trials, and advances in applied (translational) research. The journal features innovative, multimodality approaches to the diagnosis and risk stratification of cardiovascular disease. Modalities covered include echocardiography, cardiac computed tomography, cardiac magnetic resonance imaging and spectroscopy, magnetic resonance angiography, cardiac positron emission tomography, noninvasive assessment of vascular and endothelial function, radionuclide imaging, molecular imaging, and others. Article types considered by Circulation: Cardiovascular Imaging include Original Research, Research Letters, Advances in Cardiovascular Imaging, Clinical Implications of Molecular Imaging Research, How to Use Imaging, Translating Novel Imaging Technologies into Clinical Applications, and Cardiovascular Images.
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