Toxicity effects of hexavalent chromium on hematological, biochemical and digestive enzyme profiles of Labeo rohita (Hamilton, 1822).

IF 2.4 4区环境科学与生态学 Q2 ECOLOGY Ecotoxicology Pub Date : 2024-10-21 DOI:10.1007/s10646-024-02815-2

Archisman Ray, Debashri Mondal, Nabanita Chakraborty, Shreyosree Ganguly

{"title":"Toxicity effects of hexavalent chromium on hematological, biochemical and digestive enzyme profiles of Labeo rohita (Hamilton, 1822).","authors":"Archisman Ray, Debashri Mondal, Nabanita Chakraborty, Shreyosree Ganguly","doi":"10.1007/s10646-024-02815-2","DOIUrl":null,"url":null,"abstract":"The study provides a descriptive understanding of the toxic effect of heavy metal chromium on the hematological, biochemical, and digestive enzyme profiles in the fingerlings of Labeo rohita. The 96-h LC50 of hexavalent chromium was found to be 15.76 mg/L. Further, the toxicity study was conducted with four different sub-lethal concentrations of 96-h LC50 viz. 1/40th, 1/20th, 1/10th, and 1/5th respectively. The blood samples from the control and treated groups exposed to different concentrations were examined for various physiological parameters. The obtained data showed that, with the increase in sub-lethal concentration, a significant decrease (p < 0.05) in red blood cell (RBCs), hemoglobin (Hb), and hematocrit (Hct) was observed, while total white blood cell (WBCs), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) increased significantly (p < 0.05) in all the treatments. Fishes exposed to chromium for 30 days responded by becoming hyperglycemic, hyperproteineric, and hypoalbuminemia with a gradual rise in concentrations. Alteration in the intestinal digestive enzyme profiles was also observed after 30 days of study. The activity of protease (89.76%), and amylase (41.88%) decreased in the intestine with the highest concentration compared to the control. Conversely, compared to the control, the highest concentration resulted in an increase (146%) in lipase activity. Overall, this study has greatly enhanced our comprehension of the impact of chromium toxicity on various hematological, biochemical, and digestive enzyme parameters in Labeo rohita.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ecotoxicology","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1007/s10646-024-02815-2","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ECOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

The study provides a descriptive understanding of the toxic effect of heavy metal chromium on the hematological, biochemical, and digestive enzyme profiles in the fingerlings of Labeo rohita. The 96-h LC₅₀ of hexavalent chromium was found to be 15.76 mg/L. Further, the toxicity study was conducted with four different sub-lethal concentrations of 96-h LC₅₀ viz. 1/40th, 1/20th, 1/10th, and 1/5th respectively. The blood samples from the control and treated groups exposed to different concentrations were examined for various physiological parameters. The obtained data showed that, with the increase in sub-lethal concentration, a significant decrease (p < 0.05) in red blood cell (RBCs), hemoglobin (Hb), and hematocrit (Hct) was observed, while total white blood cell (WBCs), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) increased significantly (p < 0.05) in all the treatments. Fishes exposed to chromium for 30 days responded by becoming hyperglycemic, hyperproteineric, and hypoalbuminemia with a gradual rise in concentrations. Alteration in the intestinal digestive enzyme profiles was also observed after 30 days of study. The activity of protease (89.76%), and amylase (41.88%) decreased in the intestine with the highest concentration compared to the control. Conversely, compared to the control, the highest concentration resulted in an increase (146%) in lipase activity. Overall, this study has greatly enhanced our comprehension of the impact of chromium toxicity on various hematological, biochemical, and digestive enzyme parameters in Labeo rohita.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

六价铬对 Labeo rohita（汉密尔顿，1822 年）血液学、生物化学和消化酶谱的毒性效应。

该研究描述性地了解了重金属铬对鲮鱼幼鱼血液学、生物化学和消化酶谱的毒性影响。研究发现，六价铬的 96 小时半数致死浓度为 15.76 毫克/升。此外，毒性研究还采用了四种不同的亚致死浓度（96 小时半致死浓度分别为 1/40、1/20、1/10 和 1/5）。对暴露于不同浓度的对照组和处理组的血液样本进行了各种生理参数的检测。所得数据显示，随着亚致死浓度的增加，对照组和处理组的血液样本中的各种生理指标都有显著下降（p

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Ecotoxicology 环境科学-毒理学

CiteScore

5.30

自引率

3.70%

发文量

107

审稿时长

4.7 months

期刊介绍： Ecotoxicology is an international journal devoted to the publication of fundamental research on the effects of toxic chemicals on populations, communities and terrestrial, freshwater and marine ecosystems. It aims to elucidate mechanisms and processes whereby chemicals exert their effects on ecosystems and the impact caused at the population or community level. The journal is not biased with respect to taxon or biome, and papers that indicate possible new approaches to regulation and control of toxic chemicals and those aiding in formulating ways of conserving threatened species are particularly welcome. Studies on individuals should demonstrate linkage to population effects in clear and quantitative ways. Laboratory studies must show a clear linkage to specific field situations. The journal includes not only original research papers but technical notes and review articles, both invited and submitted. A strong, broadly based editorial board ensures as wide an international coverage as possible.