Phenolization of the sinus tract in recurrent sacrococcygeal pilonidal sinus disease: long-term results of a prospective cohort study.

IF 2.5 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY International Journal of Colorectal Disease Pub Date : 2024-10-18 DOI:10.1007/s00384-024-04742-4
Jochem de Kort, Akke Pronk, Menno R Vriens, Niels Smakman, Edgar J B Furnee
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Abstract

Aim: In recent years, the paradigm for the treatment of sacrococcygeal pilonidal sinus disease (SPSD) has shifted from surgical excision toward more minimally invasive techniques. Although extensive research has been conducted on the minimal invasive phenolization technique for primary SPSD, literature in recurrent SPSD is lacking. The purpose of this study was to report the long-term outcomes of the phenolization technique for recurrent SPSD.

Method: This study included all 57 patients who were initially prospectively included in this study for short-term follow-up after phenolization for recurrent SPSD. A questionnaire was sent out to all patients to obtain long-term outcome. The primary endpoint was recurrence. Secondary endpoints included quality of life and symptoms related to SPSD.

Results: A total of 47 patients (82.5%) were available for long-term follow-up. Recurrence needing further surgery developed in 7 patients (14.9%) after a mean follow-up of 76 (SD 21.7) months. At follow-up, there was improvement in the quality of life compared to preoperative levels (82.0, IQR 75.0-90.0 versus 74.0 IQR 52.5-80.0, p = 0.024). Additionally, symptoms associated with SPSD, including pain, fluid discharge, and itching sensation, also showed significant improvement. A total of 42 patients (89.4%) would undergo the same treatment again. No significant association was found between known risk factors and recurrence.

Conclusion: Phenolization for recurrent SPSD showed a recurrence rate of 14.9% with significant improvement of natal cleft symptoms and quality of life at long-term follow-up. Therefore, phenolization should be considered as a feasible option for patients with recurrent SPSD.

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复发性骶尾部朝天鼻窦疾病的窦道酚化:一项前瞻性队列研究的长期结果。
目的:近年来,治疗骶尾部朝天鼻窦疾病(SPSD)的模式已从手术切除转向更微创的技术。尽管针对原发性 SPSD 的微创酚化技术已开展了大量研究,但有关复发性 SPSD 的文献却十分缺乏。本研究旨在报告苯酚化技术治疗复发性 SPSD 的长期疗效:本研究纳入了所有57名患者,这些患者最初被前瞻性纳入本研究,接受复发性SPSD苯酚化术后的短期随访。向所有患者发放了调查问卷,以了解长期疗效。主要终点是复发。次要终点包括生活质量和与SPSD相关的症状:共有47名患者(82.5%)接受了长期随访。平均随访 76 个月(标准差 21.7 个月)后,有 7 名患者(14.9%)复发,需要进一步手术治疗。随访期间,患者的生活质量与术前相比有所改善(82.0,IQR 75.0-90.0 对 74.0,IQR 52.5-80.0,P = 0.024)。此外,与 SPSD 相关的症状,包括疼痛、液体排出和瘙痒感,也有明显改善。共有 42 名患者(89.4%)愿意再次接受同样的治疗。已知的风险因素与复发无明显关联:苯酚化疗治疗复发性 SPSD 的复发率为 14.9%,但在长期随访中,产裂症状和生活质量均有明显改善。因此,苯酚化疗应被视为复发性SPSD患者的可行选择。
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来源期刊
CiteScore
4.90
自引率
3.60%
发文量
206
审稿时长
3-8 weeks
期刊介绍: The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies. The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.
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