Management of drop attacks in Ménière's disease: a systematic literature review.

IF 0.8 4区医学 Q3 OTORHINOLARYNGOLOGY Journal of Laryngology and Otology Pub Date : 2025-06-01 DOI:10.1017/S0022215124001439

Anya Selwyn, Iain Mckay-Davies

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Abstract

Objectives: Drop attacks are described as an instantaneous fall to the ground, occurring without warning and without loss of consciousness, a consequence of abrupt deformation of the otolithic membrane due to high endolymphatic pressure. Drop attacks present significant injury risk, therefore effective treatment is imperative. This review is the first to examine all evidence for the management of drop attacks in Ménière's disease, and make recommendations.

Methods: We conducted a systematic literature review. Inclusion criteria consisted of all published English language examining treatments of drop attacks in Ménière's disease.

Results: One hundred and five articles were identified, 19 met criteria (case series and/or cohort studies). Two articles identified conservative treatments, eight examined intratympanic gentamicin, seven examined surgery, one examined all three and one examined intratympanic dexamethasone.

Conclusion: Evidence for the management of drop attacks in Ménière's disease is limited due to small studies. Some surgical approaches have limited effect. Intratympanic dexamethasone remains a promising treatment; further research is recommended.

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梅尼埃病滴水发作的管理：系统性文献综述。

目的：跌落攻击被描述为瞬间跌落到地面，在没有任何警告和意识丧失的情况下发生，是由于高内淋巴压力导致耳石膜突然变形的结果。跌落攻击存在严重的伤害风险，因此有效的治疗是必要的。这篇综述是第一次审查所有证据，以管理msamimni病的下降发作，并提出建议。方法：我们进行了系统的文献综述。纳入标准包括所有已发表的英文文献，研究了membrolizine病的治疗方法。结果：纳入了105篇文章，其中19篇符合标准（病例系列和/或队列研究）。两篇文章研究了保守治疗，八篇研究了鼓内庆大霉素，七篇研究了手术，一篇研究了这三种治疗方法，一篇研究了鼓内地塞米松。结论：由于研究规模小，关于治疗msamimni病滴发作的证据有限。一些手术入路效果有限。鼓室内地塞米松仍然是一种有希望的治疗方法；建议进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Laryngology and Otology 医学-耳鼻喉科学

CiteScore

3.20

自引率

11.80%

发文量

593

审稿时长

3-6 weeks

期刊介绍： The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.