Treatment and Management of Anaplastic Thyroid Carcinoma: Appraisal of Clinical Practice Guidelines.

IF 1.1 4区医学 Q3 OTORHINOLARYNGOLOGY Journal of Laryngology and Otology Pub Date : 2024-10-21 DOI:10.1017/S0022215124001087

Jonathan P Kuriakose, Najm Khan, Neeraj V Suresh, Emma De Ravin, Alvaro Moreira, Karthik Rajasekaran

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Abstract

Objective: To appraise clinical practice guidelines for anaplastic thyroid carcinoma treatment and management using the Appraisal of Guidelines for Research and Evaluation II tool.

Methods: A literature search was performed using MEDLINE/PubMed, Embase, Scopus, Cochrane, and Google Scholar. Four reviewers evaluated clinical practice guidelines utilising Appraisal of Guidelines for Research and Evaluation II, with domain scores requiring a threshold of greater than 60 per cent. Inter-reviewer agreement was evaluated using intraclass correlation coefficients.

Results: Twelve clinical practice guidelines were evaluated after application of inclusion and exclusion criteria. There were two "high-", four "average-", and six "low-" quality clinical practice guidelines. The domains with the highest scores were "clarity of presentation" (69.44 ± 16.75) and "scope and purpose" (68.87 ± 20.88), while "applicability" (7.12 ± 6.17) and "rigor of development" (50.26 ± 20.77) had the lowest scores. Intraclass correlation coefficients showed a high level of inter-reviewer agreement (0.689-0.924; good-excellent).

Conclusion: These results showcased wide variability in quality amongst guidelines for the treatment and management of anaplastic thyroid carcinoma. These findings necessitate greater standardisation among clinical practice guidelines and greater focus on the applicability of recommended practices.

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甲状腺无节细胞癌的治疗和管理：临床实践指南评估》。

目的：应用《研究与评价指南ⅱ》评价甲状腺间变性癌治疗与管理的临床实践指南。方法：通过MEDLINE/PubMed、Embase、Scopus、Cochrane和谷歌Scholar进行文献检索。四名审稿人使用《研究与评估指南评估II》评估临床实践指南，领域评分要求阈值大于60%。审稿人间的一致性使用类内相关系数进行评估。结果：应用纳入和排除标准对12条临床实践指南进行评价。有两个“高”，四个“一般”和六个“低”质量的临床实践指南。得分最高的是“表述清晰性”（69.44±16.75）和“范围与目的”（68.87±20.88），得分最低的是“适用性”（7.12±6.17）和“开发严谨性”（50.26±20.77）。类内相关系数显示高水平的审稿人间一致性(0.689-0.924；好)。结论：这些结果显示了甲状腺间变性癌治疗和管理指南的质量差异很大。这些发现需要在临床实践指南之间进行更大的标准化，并更加关注推荐做法的适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Laryngology and Otology 医学-耳鼻喉科学

CiteScore

3.20

自引率

11.80%

发文量

593

审稿时长

3-6 weeks

期刊介绍： The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.