Maternal and neonatal outcomes of congenital syphilis at a tertiary care center in Turkey; a retrospective observational study.

IF 0.9 4区医学 Q4 OBSTETRICS & GYNECOLOGY Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-10-19 DOI:10.1080/01443615.2024.2417251

Hasan Berkan Sayal, And Yavuz, Busra Tsakir, Erzat Toprak, Orkun Han, Hasan Ali Inal

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Abstract

Background: Maternal syphilis (MS) can lead to significant maternal morbidity and neonatal morbidity and mortality if inadequately treated. This study is aimed to retrospectively analyse the maternal and neonatal outcomes of pregnant women diagnosed with MS at our clinic.

Materials and methods: We accessed the medical records of 64 cases diagnosed with MS between 2020 and 2022 from our hospital database and the perinatology clinic archives in this retrospective observational study. Case distributions by years, sociodemographic characteristics, and maternal and neonatal outcomes were recorded.

Results: The distribution of MS cases was 16 (25.0%) in 2020, 20 (31.25%) in 2021, and 28 (43.75%) in 2022. The mean age of the patients was 26.4 ± 6.3 years, mean BMI was 23.36 ± 3.14, the smoking rate was 31.25%, and the majority of patients were educated to primary level (37.5%). Most were housewives (43.75%), lived in urban areas (43.75%), and had lower-level incomes (68.75%). In addition, 43.75% received adequate maternal treatment, the caesarean delivery rate was 43.25%, 31.25% had preterm births, and the mean birth weight was 2956.36 + 514.46 g. CS was largely diagnosed during delivery or the postpartum period (43.75%). Fifty percent of patients were in the latent stage, gestational hypertension and preeclampsia were present in four case each (6.25%), and gestational diabetes mellitus in eight (12.5%). Twenty babies (31.25%) were admitted to the neonatal intensive care unit, eight (12.5%) had congenital anomalies, 12 had foetal growth restriction (18.25%), stillbirth was present in four (6.25%) case, and early neonatal death in four (6.25%).

Conclusions: Delayed diagnosis and inadequate treatment of MS can lead to significant maternal and neonatal morbidity and mortality. Well-planned antenatal care services should be provided for all expectant mothers in order to reduce these adverse outcomes.

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土耳其一家三级医疗中心先天性梅毒的产妇和新生儿结局；一项回顾性观察研究。

背景：孕产妇梅毒（MS）如果治疗不当，可导致严重的孕产妇发病率、新生儿发病率和死亡率。本研究旨在回顾性分析本诊所确诊为梅毒孕妇的孕产妇和新生儿结局：在这项回顾性观察研究中，我们从医院数据库和围产期门诊档案中调取了2020年至2022年期间确诊为多发性硬化症的64例病例的医疗记录。研究记录了病例的年份分布、社会人口学特征、孕产妇和新生儿结局：多发性硬化症病例的分布情况为：2020 年 16 例（25.0%），2021 年 20 例（31.25%），2022 年 28 例（43.75%）。患者的平均年龄为（26.4 ± 6.3）岁，平均体重指数为（23.36 ± 3.14），吸烟率为 31.25%，大多数患者受过小学教育（37.5%）。大多数患者是家庭主妇（43.75%），居住在城市地区（43.75%），收入水平较低（68.75%）。此外，43.75%的产妇接受了适当的治疗，剖腹产率为 43.25%，31.25%为早产，平均出生体重为 2956.36 + 514.46 克。大部分产妇是在分娩过程中或产后确诊的（43.75%）。50%的患者处于潜伏期，妊娠高血压和子痫前期各占 4 例（6.25%），妊娠糖尿病占 8 例（12.5%）。20名婴儿（31.25%）被送进新生儿重症监护室，8名婴儿（12.5%）患有先天性畸形，12名婴儿（18.25%）患有胎儿生长受限，4名婴儿（6.25%）死胎，4名婴儿（6.25%）新生儿早期死亡：结论：多发性硬化症的诊断延迟和治疗不当可导致严重的孕产妇和新生儿发病率和死亡率。结论：多发性硬化症的延误诊断和治疗不当可导致严重的孕产妇和新生儿发病率和死亡率，应为所有孕妇提供计划周全的产前护理服务，以减少这些不良后果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Obstetrics and Gynaecology 医学-妇产科学

CiteScore

2.40

自引率

7.70%

发文量

398

审稿时长

6 months

期刊介绍： Journal of Obstetrics and Gynaecology represents an established forum for the entire field of obstetrics and gynaecology, publishing a broad range of original, peer-reviewed papers, from scientific and clinical research to reviews relevant to practice. It also includes occasional supplements on clinical symposia. The journal is read widely by trainees in our specialty and we acknowledge a major role in education in Obstetrics and Gynaecology. Past and present editors have recognized the difficulties that junior doctors encounter in achieving their first publications and spend time advising authors during their initial attempts at submission. The journal continues to attract a world-wide readership thanks to the emphasis on practical applicability and its excellent record of drawing on an international base of authors.