Middle meningeal artery embolization in chronic subdural hematoma.

IF 0.6 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Medicina-buenos Aires Pub Date : 2024-01-01
Carlos G Videla, Libardo Valencia Chicue, Ana L Colomer, Miguel Villaescusa, Pablo Ajler, Nicolás M Ciarrocchi
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Abstract

Chronic subdural hematoma (cSDH) is an increasingly prevalent condition, particularly among elderly population and is associated with elevated morbidity. The pathophysiology of cSDH involves proliferation of dural edge cells, fibroblasts, and release of vascular angiogenic factors leading to angiogenesis of a vascularized neomembrane perfused by the middle meningeal artery (MMA). MMA embolization is a technique that can be employed as treatment in conjunction with surgery or as a standalone therapy. Our aim is to describe our experience with treating selective cSDH patients with embolization of MMA in a university hospital in Argentina. We deployed this procedure in 6 patients over a period of one year and a half years with a median age of 72.5, with a median SDH thickness of 12.5 mm and four of them had a midline deviation greater than 5mm. The decision of the embolization was done due to minor symptoms and the necessity of restart antiplatelet therapy or anticoagulation, formal contraindication for surgery or as adjuvant of surgery because of cSDH recurrence. After discharge, no patient required a new surgical intervention. MMA embolization is impressive to be a safe and an option to treat cSDH. We present our experience in six patients in a hospital in Argentina.

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慢性硬膜下血肿的脑膜中动脉栓塞术。
慢性硬膜下血肿(cSDH)的发病率越来越高,尤其是在老年人群中,而且与发病率升高有关。cSDH 的病理生理学涉及硬脑膜边缘细胞、成纤维细胞的增殖和血管生成因子的释放,从而导致由脑膜中动脉(MMA)灌注的血管化新膜的血管生成。脑膜中动脉栓塞是一种可与手术结合使用的治疗技术,也可作为一种独立疗法。我们的目的是介绍阿根廷一家大学医院采用 MMA 栓塞治疗选择性 cSDH 患者的经验。在一年半的时间里,我们为 6 名患者实施了这种手术,患者的中位年龄为 72.5 岁,中位 SDH 厚度为 12.5 毫米,其中 4 人的中线偏差超过 5 毫米。决定进行栓塞治疗的原因包括症状轻微、需要重新开始抗血小板治疗或抗凝治疗、手术正式禁忌症或因 cSDH 复发而作为手术的辅助治疗。出院后,没有患者需要进行新的手术治疗。令人印象深刻的是,MMA 栓塞是治疗 cSDH 的一种安全选择。我们介绍了阿根廷一家医院对六名患者的治疗经验。
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来源期刊
Medicina-buenos Aires
Medicina-buenos Aires 医学-医学:内科
CiteScore
1.30
自引率
12.50%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Information not localized
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