Addressing Challenges in Antibiotic Access: Barriers, Implications and Strategies for Solution.

IF 3.1 Q2 PHARMACOLOGY & PHARMACY Pharmaceutical Medicine Pub Date : 2024-10-19 DOI:10.1007/s40290-024-00538-7

Ritika Kondel Bhandari, Avaneesh Kumar Pandey, Samir Malhotra, Ashish Kumar Kakkar, Sanjeev Singh, Jennifer Cohn, Alison Holmes, Esmita Charani, Nusrat Shafiq

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Abstract

Antimicrobial resistance (AMR) poses a significant threat to global public health, disproportionately affecting low- and middle-income countries (LMICs). While excessive antibiotic use is often discussed, the issue of access to antibiotics demands attention. This viewpoint explores the multidimensional nature of the issue of access to antibiotics. We have examined the issue through the lens of social, economic, healthcare structures, manufacturing and supply chain, policy and practices. Inter-relatedness of these issues has also been explored. The review further discusses potential solutions involving but not limited to increased awareness, improvement in healthcare infrastructure, models for sustained manufacturing and supply chains. Additionally, enhancing antimicrobial stewardship at hospital and community levels, empowering healthcare professionals, and emphasizing infection prevention are crucial. Global initiatives that aim to address access challenges, emphasizing collaboration and innovation are important to foster for a sustained response to the issue of antibiotic access.

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应对抗生素获取方面的挑战：障碍、影响和解决策略。

抗菌药耐药性（AMR）对全球公共卫生构成重大威胁，对中低收入国家（LMICs）的影响尤为严重。虽然人们经常讨论过度使用抗生素的问题，但获得抗生素的问题也需要关注。这一观点探讨了抗生素获取问题的多面性。我们从社会、经济、医疗保健结构、生产和供应链、政策和实践等角度对这一问题进行了研究。我们还探讨了这些问题之间的相互关联性。审查进一步讨论了潜在的解决方案，包括但不限于提高认识、改善医疗保健基础设施、持续生产和供应链模式。此外，在医院和社区层面加强抗菌药物管理、增强医疗保健专业人员的能力以及强调感染预防也至关重要。旨在应对抗生素获取挑战、强调合作与创新的全球倡议对于促进持续应对抗生素获取问题非常重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmaceutical Medicine PHARMACOLOGY & PHARMACY-

CiteScore

5.10

自引率

4.00%

发文量

期刊介绍： Pharmaceutical Medicine is a specialist discipline concerned with medical aspects of the discovery, development, evaluation, registration, regulation, monitoring, marketing, distribution and pricing of medicines, drug-device and drug-diagnostic combinations. The Journal disseminates information to support the community of professionals working in these highly inter-related functions. Key areas include translational medicine, clinical trial design, pharmacovigilance, clinical toxicology, drug regulation, clinical pharmacology, biostatistics and pharmacoeconomics. The Journal includes:Overviews of contentious or emerging issues.Comprehensive narrative reviews that provide an authoritative source of information on topical issues.Systematic reviews that collate empirical evidence to answer a specific research question, using explicit, systematic methods as outlined by PRISMA statement.Original research articles reporting the results of well-designed studies with a strong link to wider areas of clinical research.Additional digital features (including animated abstracts, video abstracts, slide decks, audio slides, instructional videos, infographics, podcasts and animations) can be published with articles; these are designed to increase the visibility, readership and educational value of the journal’s content. In addition, articles published in Pharmaceutical Medicine may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand important medical advances.All manuscripts are subject to peer review by international experts. Letters to the Editor are welcomed and will be considered for publication.