Agminated Eruptive Melanocytic Nevi and Nail Changes Following Toxic Epidermal Necrolysis in a Pediatric Patient: A Case Report and Systematic Review of the Literature.

IF 1.2 4区 医学 Q3 DERMATOLOGY Pediatric Dermatology Pub Date : 2025-03-01 Epub Date: 2024-10-10 DOI:10.1111/pde.15777
Scott C Jaros, Dean S Morrell, Elizabeth L Nieman
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Abstract

Eruptive melanocytic nevi (EMN) have been reported in the setting of immunosuppression, chemotherapy, and bullous skin disease, including less commonly, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). This case report presents a 4-year-old girl who developed agminated EMN and nail changes after TEN. A systematic review of the literature supports clinically appropriate follow-up of EMN, as there is no reports of malignancy in EMN following SJS/TEN, nor reports of pediatric melanoma arising within EMN of any etiology. Further study of the possible correlation of nail changes with the development of EMN and better characterization of the dermoscopic features of EMN could improve monitoring and care of these patients.

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一名儿科患者中毒性表皮坏死溶解后的播散性爆发性黑素细胞痣和指甲变化:病例报告和文献系统性综述。
据报道,爆发性黑素细胞痣(EMN)可在免疫抑制、化疗和牛皮癣(包括较少见的史蒂文斯-约翰逊综合征(SJS)和中毒性表皮坏死(TEN))的情况下出现。本病例报告介绍了一名 4 岁女孩在 TEN 后出现的带状 EMN 和指甲变化。对文献的系统性回顾支持对 EMN 进行适当的临床随访,因为目前还没有关于 SJS/TEN 后 EMN 发生恶性肿瘤的报道,也没有关于任何病因引起的小儿黑色素瘤的报道。进一步研究指甲变化与 EMN 发生的可能相关性,并更好地描述 EMN 的皮肤镜特征,可以改善对这些患者的监测和护理。
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来源期刊
Pediatric Dermatology
Pediatric Dermatology 医学-皮肤病学
CiteScore
3.20
自引率
6.70%
发文量
269
审稿时长
1 months
期刊介绍: Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.
期刊最新文献
Diagnosis and Management of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Systematic Review of Clinical Guidelines and Consensus Statements. Enteral Green Beans in the Management of Neonatal Irritant Diaper Dermatitis. Racial Differences in Dermatologic Treatment for Adolescents With PCOS-Related Acne Vulgaris. The Inpatient Burden of Pediatric Dermatology in the United States: A National Analysis of the 2022 Kids' Inpatient Database. Neonatal Herpes Simplex Infection With Extensive Congenital Epidermal Skin Loss: A Report of Four Cases.
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