Pulmonary arteriovenous malformation in children.

IF 2.3 3区 医学 Q1 PEDIATRICS Pediatric Pulmonology Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI:10.1002/ppul.27354
A Y L Lim, F Ratjen
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Abstract

Pulmonary arteriovenous malformations (PAVMs) are rare abnormalities observed mainly in children with hereditary haemorrhagic telangiectasia (HHT). A majority of patients are asymptomatic at the time of detection. However, complications such as hypoxemia, stroke, cerebral abscess and massive hemoptysis can arise if larger PAVMs remain untreated. Larger PAVMs are usually managed successfully with embolization, although reperfusion of PAVMs have been reported post procedure. Early screening for PAVMs is recommended in asymptomatic children with HHT or those at risk for HHT. Longer term surveillance is also essential, to enable timely identification and management of PAVMs.

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儿童肺动静脉畸形。
肺动静脉畸形(PAVM)是一种罕见的畸形,主要见于遗传性出血性毛细血管扩张症(HHT)患儿。大多数患者在发现时并无症状。但是,如果较大的海绵状血管瘤得不到治疗,就会出现低氧血症、中风、脑脓肿和大咯血等并发症。较大的 PAVM 通常可通过栓塞手术成功治愈,但也有 PAVM 术后再灌注的报道。建议对无症状的 HHT 患儿或有 HHT 风险的患儿进行 PAVM 早期筛查。长期监测也很重要,以便及时发现和处理 PAVM。
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来源期刊
Pediatric Pulmonology
Pediatric Pulmonology 医学-呼吸系统
CiteScore
6.00
自引率
12.90%
发文量
468
审稿时长
3-8 weeks
期刊介绍: Pediatric Pulmonology (PPUL) is the foremost global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. Combining explicit and informative analysis of clinical as well as basic scientific research, PPUL provides a look at the many facets of respiratory system disorders in infants and children, ranging from pathological anatomy, developmental issues, and pathophysiology to infectious disease, asthma, cystic fibrosis, and airborne toxins. Focused attention is given to the reporting of diagnostic and therapeutic methods for neonates, preschool children, and adolescents, the enduring effects of childhood respiratory diseases, and newly described infectious diseases. PPUL concentrates on subject matters of crucial interest to specialists preparing for the Pediatric Subspecialty Examinations in the United States and other countries. With its attentive coverage and extensive clinical data, this journal is a principle source for pediatricians in practice and in training and a must have for all pediatric pulmonologists.
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