Clinical-pathological correlation of various symptoms in the diagnosis of pediatric eosinophilic esophagitis.

Abstract

Eosinophilic esophagitis (EoE) is an immune-mediated disorder of the esophagus with a broad spectrum of clinical presentations. Dysphagia and food impaction are the cardinal symptoms; however, their diagnostic utility remains controversial in pediatric populations. This study evaluates the clinical-pathological association of different symptoms with EoE. We conducted an analytical study of patients under 15 years of age who underwent esophagoscopy at a pediatric hospital between 2015 and 2022 due to suspected EoE (Reg. 341E/2023). The prevalence of various symptoms and medical histories was compared, along with their association with histopathological abnormalities, between patients with EoE and those without the disease (NEoE). A total of 24 EoE patients and 17 NEoE children were included.