IgG antibody level to mycobacterial glycoprotein in pulmonary tuberculosis by ELISA.

K Kato, K Yamamoto, M Shibata, S Kurematsu, O Mitsuhashi, A Kuze
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Abstract

Sera from patients with active pulmonary tuberculosis and sera from appropriate control individuals were assayed for IgG, IgA and IgM antibodies against glycoprotein from tubercle bacilli by an enzyme-linked immunosorbent assay. The mean antibody levels in IgG and IgA were significantly higher in the tuberculosis patients than in the controls. By measuring IgG antibody, this assay may provide a diagnostic tool to distinguish patients with active pulmonary tuberculosis from patients with other pulmonary disease.

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ELISA检测结核分枝杆菌糖蛋白IgG抗体水平。
采用酶联免疫吸附法检测活动性肺结核患者血清和相应对照血清中抗结核杆菌糖蛋白的IgG、IgA和IgM抗体。结核患者IgG和IgA的平均抗体水平明显高于对照组。通过检测IgG抗体,本试验可为区分活动性肺结核患者和其他肺部疾病患者提供一种诊断工具。
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