Pyeloplasty for the treatment of ectopic renal hydronephrosis in adults: a case series of six patients.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-09-30 Epub Date: 2024-09-26 DOI:10.21037/tau-24-142
Wencong Han, Zhihua Li, Guanpeng Han, Liqing Xu, Xinfei Li, Shubo Fan, Bing Wang, Chen Huang, Yuanshan Cui, Zheng Zhang, Liqun Zhou, Kunlin Yang, Xuesong Li
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Abstract

Background: Ectopic renal hydronephrosis is a relatively rare condition, with literature primarily consisting of scattered case studies. The ectopic kidney poses technical challenges to surgeons due to its structural and anatomical abnormalities. This study aims to share our initial experiences with minimally invasive pyeloplasty as a management approach for ectopic renal hydronephrosis in adult patients.

Case description: Between August 2018 and January 2023, six patients underwent minimally invasive pyeloplasty for ectopic kidneys. The patient cohort consisted of four individuals with pelvic kidneys, one with an iliac kidney, and one with an abdominal kidney. Among these, three cases were left-sided, two were right-sided, and one was isolated. The median patient age was 27 (range, 18-45) years. Four patients underwent robot-assisted laparoscopic pyeloplasty, while two underwent laparoscopic pyeloplasty. The median operative time was 134 (range, 63-240) minutes. After a median follow-up duration of 28.5 (range, 6-59) months, two patients required nephrectomy, with vesicoureteral reflux (VUR) and malrotation potentially contributing to surgical failure in these cases. The remaining four patients showed either stable or improved hydronephrosis and renal function. The overall operative success rate was 66.7%.

Conclusions: The rarity and anatomical variations of ectopic kidneys hinder the standardization of surgical approaches. The integration of three-dimensional (3D) virtual reconstruction and tailored surgical techniques contributes to enhanced outcomes in ectopic renal hydronephrosis cases. Furthermore, continued research and refinement of surgical approaches are needed.

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肾盂成形术治疗成人异位肾积水:六例患者的病例系列。
背景:异位肾积水是一种相对罕见的疾病,文献主要包括零散的病例研究。由于异位肾的结构和解剖异常,给外科医生带来了技术上的挑战。本研究旨在分享我们将微创肾盂成形术作为成人患者异位肾积水治疗方法的初步经验:2018 年 8 月至 2023 年 1 月间,6 名患者因异位肾接受了微创肾盂成形术。患者队列中,4人患有盆腔肾,1人患有髂肾,1人患有腹腔肾。其中,三例为左侧肾,两例为右侧肾,一例为孤立肾。患者年龄中位数为 27 岁(18-45 岁)。四名患者接受了机器人辅助腹腔镜肾盂成形术,两名患者接受了腹腔镜肾盂成形术。中位手术时间为 134 分钟(63-240 分钟)。中位随访时间为 28.5 个月(6-59 个月),两名患者需要进行肾切除术,膀胱输尿管反流(VUR)和肾旋转不良可能是导致手术失败的原因。其余四名患者的肾积水和肾功能均趋于稳定或有所改善。总体手术成功率为 66.7%:结论:异位肾的罕见性和解剖变异阻碍了手术方法的标准化。三维(3D)虚拟重建和定制手术技术的整合有助于提高异位肾积水病例的治疗效果。此外,还需要继续研究和改进手术方法。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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