The Potential of Tendon Autograft as Meniscus substitution: Current concepts.

Youngji Kim, Eriksson Karl, Muneaki Ishijima, Sylvain Guy, Christophe Jacquet, Matthieu Ollivier
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Abstract

Meniscectomy is known to alter the mechanics, stability, and kinematics of the tibiofemoral joint, leading to early knee osteoarthritis (KOA). While several meniscal substitutions exist, such as meniscus allograft transplantation, collagen meniscus implants, and artificial substitutes, they often come with technical challenges, high costs, and risks, including allograft failure, infections, and disease transmission. Tendon autografts emerge as a promising option, offering safety, availability, biocompatibility, and a reduced risk of pathophoresis. This review delves into basic, in vivo, in vitro, and biomechanical studies alongside clinical outcomes and future prospects of tendon autografts as meniscus substitutes. A thorough understanding of this option is vital for integrating these evolving techniques into clinical practice and mitigating early KOA progression.

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肌腱自体移植作为半月板替代物的潜力:当前概念。
众所周知,半月板切除术会改变胫股关节的力学、稳定性和运动学,导致早期膝关节骨性关节炎(KOA)。虽然存在多种半月板替代物,如半月板同种异体移植、胶原半月板植入物和人工替代物,但这些替代物往往存在技术难题、高成本和风险,包括同种异体移植失败、感染和疾病传播。肌腱自体移植物具有安全性、可用性、生物相容性和较低的病理渗透风险,是一种很有前景的选择。本综述深入探讨了肌腱自体移植物作为半月板替代物的基础、体内、体外和生物力学研究,以及临床结果和未来前景。透彻了解这一选择对于将这些不断发展的技术融入临床实践和减轻早期 KOA 进展至关重要。
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来源期刊
CiteScore
2.90
自引率
6.20%
发文量
61
审稿时长
108 days
期刊最新文献
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