Validation of a Simplified Laboratory-Based HCV Clearance Definition Using New York City Hepatitis C Program and Surveillance Data.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Public Health Management and Practice Pub Date : 2024-10-16 DOI:10.1097/PHH.0000000000002077

Christina S Hwang, Martha P Montgomery, Diana I Diaz Munoz, Shaoman Yin, Eyasu H Teshale, Angelica Bocour

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Abstract

Context: Laboratory-based hepatitis C virus (HCV) clearance cascades are an important tool for health departments to track progress toward HCV elimination, but a laboratory-based definition of HCV clearance has not yet been validated.

Objective: To compare agreement between a laboratory-based HCV clearance definition with a clinical cure definition.

Design: Observational.

Setting: New York City Department of Health and Mental Hygiene HCV surveillance system data and New York City hepatitis C linkage-to-care program data.

Participants: Linkage-to-care program participants who were diagnosed with hepatitis C and enrolled in the linkage-to-care program from July 1, 2016, through June 30, 2020.

Main outcome measure: Percent agreement between a laboratory-based HCV clearance definition (surveillance system) and a clinical cure definition (program data).

Results: Among 591 program participants with known treatment outcome, the laboratory-based HCV clearance definition and clinical cure definition were concordant in 573 cases (97%).

Conclusions: A laboratory-based HCV clearance definition based on public health surveillance data can be a reliable source for monitoring HCV elimination.

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利用纽约市丙型肝炎计划和监测数据验证基于实验室的简化丙型肝炎病毒清除率定义。

背景：基于实验室的丙型肝炎病毒（HCV）清除级联是卫生部门跟踪消除 HCV 进展情况的重要工具，但基于实验室的 HCV 清除定义尚未得到验证：目的：比较实验室HCV清除定义与临床治愈定义之间的一致性：设计：观察性：背景：纽约市健康与心理卫生局丙型肝炎病毒监测系统数据和纽约市丙型肝炎联系护理计划数据：主要结果测量指标：基于实验室的丙型肝炎病毒清除定义（监测系统）与临床治愈定义（项目数据）之间的一致性百分比：结果：在已知治疗结果的 591 名项目参与者中，有 573 例（97%）基于实验室的 HCV 清除定义与临床治愈定义一致：结论：基于公共卫生监测数据的实验室HCV清除定义是监测HCV消除情况的可靠来源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Public Health Management and Practice PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.40

自引率

9.10%

发文量

287

期刊介绍： Journal of Public Health Management and Practice publishes articles which focus on evidence based public health practice and research. The journal is a bi-monthly peer-reviewed publication guided by a multidisciplinary editorial board of administrators, practitioners and scientists. Journal of Public Health Management and Practice publishes in a wide range of population health topics including research to practice; emergency preparedness; bioterrorism; infectious disease surveillance; environmental health; community health assessment, chronic disease prevention and health promotion, and academic-practice linkages.